TABLE 2.
Sex | Age | CAG repeats | CAPs | Diagnostic delay | AAO | Education attainment | Family history | TMS | TFC | Affect | Irritability | Apathy | Dysexecutive | Psychosis | HAMD | BDI | ||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
MMSE | Pearson r | 0.117 | −0.324 | 0.235 | 0.076 | −0.401 | −0.180 | 0.536 | −0.105 | −0.428 | 0.528 | −0.110 | −0.150 | −0.214 | −0.441 | 0.071 | −0.215 | −0.061 |
p Value | .134 | <.001 a | .002 a | .336 | <.001 a | .021 a | <.001 a | .179 | <.001 a | <.001 a | .178 | .064 | .008 a | <.001 a | .382 | .029 a | .581 | |
Animal VFT | Pearson r | −0.065 | −0.352 | 0.327 | 0.168 | −0.347 | −0.254 | 0.398 | 0.135 | −0.459 | 0.387 | 0.196 | −0.010 | −0.271 | −0.170 | −0.013 | 0.011 | 0.044 |
p Value | .577 | .002 a | .004 a | .144 | .002 a | .026 a | <.001 a | .240 | <.001 a | <.001 a | .088 | .929 | .017 a | .139 | .914 | .926 | .741 | |
Letter VFT | Pearson r | 0.038 | −0.308 | 0.166 | 0.001 | −0.229 | −0.118 | 0.479 | −0.079 | −0.447 | 0.348 | −0.039 | −0.144 | −0.152 | −0.149 | −0.038 | −0.123 | −0.192 |
p Value | .630 | <.001 a | .032 a | .994 | .003 a | .123 | <.001 a | .313 | <.001 a | <.001 a | .641 | .081 | .065 | .071 | .650 | .270 | .108 | |
Trail making test A | Pearson r | −0.063 | 0.448 | −0.360 | −0.124 | 0.322 | 0.409 | −0.379 | 0.030 | 0.572 | −0.460 | 0.008 | −0.043 | 0.157 | 0.243 | −0.001 | 0.152 | 0.080 |
p Value | .603 | <.001 a | .002 a | .304 | .006 a | <.001 a | .002 a | .803 | <.001 a | <.001 a | .946 | .723 | .191 | .041 a | .989 | .212 | .549 | |
Trail making test B | Pearson r | −0.199 | 0.167 | −0.116 | 0.051 | 0.112 | 0.208 | −0.159 | −0.022 | 0.355 | −0.284 | 0.126 | −0.218 | 0.097 | 0.001 | 0.002 | 0.260 | 0.140 |
p Value | .103 | .174 | .348 | .678 | .365 | .089 | .209 | .858 | .003 a | .019 a | .307 | .074 | .431 | .998 | .989 | .035 a | .309 | |
Stroop naming | Pearson r | −0.137 | −0.334 | 0.265 | 0.115 | −0.333 | −0.199 | 0.398 | −0.175 | −0.532 | 0.401 | −0.0653 | −0.150 | −0.0866 | −0.247 | −0.0374 | −0.212 | −0.0952 |
p Value | .082 | <.001 a | <.001 a | .143 | <.001 a | .011 a | <.001 a | .025 a | <.001 a | <.001 a | .431 | .068 | .296 | .003 a | .651 | .056 | .423 | |
Stroop reading | Pearson r | −0.133 | −0.432 | 0.331 | 0.117 | −0.391 | −0.300 | 0.328 | −0.0588 | −0.562 | 0.498 | −0.0316 | −0.103 | −0.200 | −0.262 | −0.0336 | −0.207 | −0.159 |
p Value | .099 | <.001 a | <.001 a | .145 | <.001 a | <.001 a | <.001 a | .466 | <.001 a | <.001 a | .708 | .222 | .017 | .002 a | .690 | .064 | .184 | |
Stroop interference | Pearson r | −0.123 | −0.168 | 0.169 | 0.103 | −0.389 | −0.0271 | 0.236 | −0.0787 | −0.467 | 0.296 | −0.151 | −0.259 | −0.191 | −0.206 | −0.103 | −0.334 | −0.256 |
p Value | .131 | .038 a | .037 a | .209 | <.001 a | .741 | .004 a | .335 | <.001 a | <.001 a | .078 | .002 a | .025 a | .015 a | .228 | .003 a | .036 a | |
SDMT | Pearson r | −0.062 | −0.445 | 0.202 | 0.387 | 0.386 | −0.355 | 0.359 | 0.116 | −0.609 | 0.619 | 0.119 | −0.165 | −0.117 | −0.320 | −0.081 | −0.188 | −0.139 |
p Value | .312 | <.001 a | .054 | <.001 a | .001 a | .002 a | .002 a | .178 | <.001 a | <.001 a | .173 | .094 | .177 | .005 a | .261 | .067 | .134 | |
HVLT‐R | Pearson r | 0.026 | −0.486 | 0.522 | 0.132 | −0.441 | −0.376 | 0.452 | 0.177 | −0.310 | 0.402 | 0.068 | −0.105 | −0.259 | −0.186 | 0.192 | −0.109 | −0.020 |
p Value | .438 | .001 a | <.001 a | .832 | .002 a | .009 a | .002 a | .140 | .028 a | .006 a | .341 | .263 | .056 | .128 | .120 | .254 | .452 |
Note: Bold p values (<.05) are statistically significant.
Abbreviations: BDI, Beck Depression Inventory; CAPs, CAG‐age‐product score; HAMD, Hamilton depression scale; HVLT‐R: Hopkins verbal learning test–revised; MMSE, mini–mental state examination; PBA‐s, short version of problem behavior assessment; SDMT, symbol digit modality test; TFC, total functional capacity scale; TMS, total motor score in the unified Huntington's disease rating scale; TMT, trail making task.