. 2023 Oct 17;13(11):e3258. doi: 10.1002/brb3.3258

TABLE 3.

Regression model results showing the association between cognitive test performance (dependent variable) and variables of interest (independent variable) adjusted for sex and age.

Neuropsychological performance (domain/test)		Variables	Standardized coefficients beta	p Value	F	R Square
Executive function	Stroop test	Sex	−0.024	.635	F = 52.20 p < .001	.55 (Adjusted R ²: .54)
		Age	−0.234	<.001 ^a
		TFC	0.345	<.001 ^a
		Education attainment	0.351	<.001 ^a
		TMS	−0.269	<.001 ^a
		AAO	−0.119	.026 ^a
Global cognition	MMSE	Sex	0.034	.531	F = 38.25 p < .001	.61 (Adjusted R ²: .60)
		Age	−0.098	.085
		Education attainment	0.363	<.001 ^a
		TMS	−0.142	.049 ^a
		TFC	0.346	<.001 ^a
		Dysexecutive	−0.227	<.001 ^a
Processing speed, executive function	TMT	Sex	−0.237	.019 ^a	F = 8.80 p < .001	.41 (Adjusted R ²: .37)
		Age	−0.024	.953
		AAO	0.355	.359
		TMS	−0.488	<.001 ^a
		Irritability	−0.226	.034 ^a
Language	VFT	Sex	0.155	.080	F = 24.44 p < .001	.60 (Adjusted R ²: .57)
		Age	−0.139	.457
		TMS	−0.544	<.001 ^a
		Education attainment	0.309	.001 ^a
		Family history	0.224	.007 ^a
		CAG	0.202	.023 ^a
Processing speed	SDMT	Sex	0.052	.679	F = 24.26 p < .001	.62 (Adjusted R ²: .59)
		Age	−0.823	.073
		TFC	0.435	<.001 ^a
		AAO	−0.300	.001 ^a
		Education attainment	0.221	.012 ^a
		TMS	−0.267	.026 ^a
Episodic memory	Total Recall	Sex	0.052	.679	F = 7.80 p < .001	.47 (Adjusted R ²: .41)
		Age	−0.139	.457
		CAG repeats	0.363	.012 ^a
		TFC	0.292	.040 ^a
		Education attainment	0.379	.004 ^a

Abbreviations: MMSE, mini–mental state examination; TFC, total functional capacity scale; TMS, total motor score in the unified Huntington's disease rating scale; SDMT, symbol digit modality test; TMT, trail making test.

^{^a}

p < .05, statistically significant.