Skip to main content
. 2023 Sep 21;15(10):5823–5843. doi: 10.21037/jtd-22-1776

Table 1. Evidence summary of cough in chronic respiratory disease.

Cough characteristics Asthma COPD Bronchiectasis ILD Sarcoidosis
Prevalence of cough 8–58% 10–74% 82–98% 50–89% 3–64%
Impact of cough ↑ GINA severity ↑ SGRQ/CAT ↑ BSI ↑ Mortality ↓ FVC#
↑ ACQ ↓ FEV1 ↑ CT severity ↑ CT severity ↓ ACE#
↓ FEV1 ↑ Exacerbations# ↑ Exacerbations ↓ FVC ↑ Dyspnoea
↑ Exacerbations ↑ Dyspnoea ↑ Sputum burden ↓ DLCO
↑ Dyspnoea ↑ Dyspnoea
Impaired QoL, LCQ range 13–18 13–19 12–16 15–17 15–17
Cough reflex sensitivity

↑, increased; ↓, decreased; , data conflicting. COPD, chronic obstructive pulmonary disease; ILD, interstitial lung disease; GINA, Global Initiative for Asthma; SGRQ, St George’s Respiratory Questionnaire; CAT, COPD Assessment Tool; BSI, Bronchiectasis Severity Index; FVC, forced vital capacity; ACQ, Asthma Control Questionnaire; FEV1, forced expiratory volume in 1 second; CT, computed tomography; ACE, angiotensin converting enzyme; DLCO, diffusing capacity of the lungs for carbon monoxide; QoL, Quality of Life; LCQ, Leicester Cough Questionnaire (range, 3–21, lower score indicates worse cough-specific health status).