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. 2023 Sep 15;15(10):5454–5465. doi: 10.21037/jtd-22-1669

Figure 3.

Figure 3

Effect of UCMNCs on airway inflammation in mice with OVA-induced asthma. The largest longitudinal section of the lung lobes was stained using HE. The airway inflammation was semi-scored from 0 (normal) to 4 (severe) based on inflammatory cell infiltration around the airway. Data are expressed as mean ± standard deviation. ##, P<0.01 vs. control group; *, P<0.05, **, P<0.01 vs. model group; n=6 for DEX group, n=8 for UCMNCH group, and n=10 for other groups. Bar =200 μm. UCMNCL, UCMNCM, and UCMNCH: intravenous injection of 4×105, 2×106, and 107 UCMNCs per mouse, respectively; FMMNC: intravenous injection of 2×106 FMMNCs per mouse. DEX, dexamethasone; UCMNC, umbilical cord blood mononuclear cell; UCMNCL, low-dose UCMNC; UCMNCM, medium-dose UCMNC; UCMNCH, high-dose UCMNC; FMMNC, fetal mouse blood mononuclear cell; OVA, ovalbumin; HE, hematoxylin and eosin.