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. 2023 Sep 15;15(10):5454–5465. doi: 10.21037/jtd-22-1669

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2023 Journal of Thoracic Disease. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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Effect of UCMNCs on CD4/CD8 lymphocyte subsets in BALF of mice with OVA-induced asthma. (A) CD4/CD8 lymphocyte cells were gating from CD3⁺CD45⁺ cells using flow cytometry. (B) Effect of UCMNCs on CD4/CD8 lymphocyte subsets in BALF. Data are expressed as mean ± standard deviation. ^##, P<0.01 vs. control group; *, P<0.05, **, P<0.01 vs. model group; n=5. UCMNC^L, UCMNC^M, and UCMNC^H: intravenous injection of 4×10⁵, 2×10⁶, and 10⁷ UCMNCs per mouse, respectively; FMMNC: intravenous injection of 2×10⁶ FMMNCs per mouse. IL, interleukin; DEX, dexamethasone; UCMNC, umbilical cord blood mononuclear cell; UCMNC^L, low-dose UCMNC; UCMNC^M, medium-dose UCMNC; UCMNC^H, high-dose UCMNC; FMMNC, fetal mouse blood mononuclear cell; BALF, bronchoalveolar lavage fluid; OVA, ovalbumin.