Table 2. Primary and secondary outcomes, respiratory parameters and postoperative conditions.
| Variables | RRALE <1 (n=9) | RRALE ≥1 (n=7) | P value |
|---|---|---|---|
| Primary outcome | |||
| 90-day mortality | 6 (66.67) | 0 | 0.01 |
| Secondary outcomes | |||
| In hospital 28-day mortality | 2 (22.22) | 0 | 0.48 |
| ICU LOS (days) | 12 [7, 18] | 7 [4, 14] | 0.34 |
| Hospital LOS (days) | 28 [19, 40] | 20 [16, 28] | 0.36 |
| Preoperative pulmonary function | |||
| MVV% | 208.2 [143.4, 274.1] | 357.5 [274.9, 437.9] | 0.11 |
| VC max% | 76.9 [66.6, 89.0] | 86.3 [27.0, 91.6] | 0.46 |
| FVC% | 79.1 [70.0, 91.8] | 91.9 [85.0, 101.3] | 0.15 |
| FEV1% | 76.9 [65.2, 91.1] | 93.5 [75.2, 114.1] | 0.28 |
| P/F ratio (mmHg) | 410.0 [381.0, 414.0] | 398.0 [364.3, 452.8] | 0.93 |
| PaCO2 (mmHg) | 40 [34, 44] | 39 [36, 43] | >0.99 |
| Postoperative fluid balance | |||
| Day 1 (mL/kg) | 6.09 [3.30, 12.67] | 1.53 [−1.86, 6.50] | 0.25 |
| Day 2 (mL/kg) | 5.22 [−4.42, 10.43] | 5.66 [−7.17, 10.16] | >0.99 |
| Day 3 (mL/kg) | 4.91 [−3.32, 10.43] | 2.32 [−2.63, 4.71] | 0.47 |
| 3 days total (mL/kg) | 16.76 [1.91, 23.44] | 9.29 [0.38, 19.64] | 0.61 |
| Onset of hypoxemia after operation (days) | 6 [3, 8] | 3 [2, 4] | 0.28 |
| Worst P/F ratio in ICU (mmHg) | 97.0 [84.0, 119.0] | 113.0 [95.0, 155.0] | 0.24 |
| Lowest PaCO2 in ICU (mmHg) | 33.0 [30.8, 39.6] | 40.0 [31.5, 45.5] | 0.35 |
| Respiratory rate (bpm) | 30.0 [24.5, 35.5] | 24.0 [20.0, 33.0] | 0.26 |
| Body temperature | |||
| Maximum (℃) | 38.7 [38.3, 38.9] | 37.6 [37.0, 37.8] | 0.03 |
| ≥38.5 ℃ | 7 (77.78) | 1 (14.29) | 0.04 |
| Invasive MV | |||
| Number | 7 (77.78) | 6 (85.71) | >0.99 |
| Duration (h) | 167.5 [97.3, 556.3] | 35.5 [21.5, 164.0] | 0.11 |
| NMBA using | 4 (44.44) | 1 (14.29) | 0.31 |
Data are presented as medians [interquartile ranges] or n (%). RRALE, RALE score ratio, RRALE = RALES/RALENS; RALE, radiographic assessment of lung edema; RALES, RALE score of surgical side; RALENS, RALE score of non-surgical side; ICU, intensive care unit; LOS, length of stay; MVV, maximal voluntary ventilation; VC max, maximum vital capacity; FVC, forced vital capacity; FEV1, forced expiratory volume in 1 second, FEV1% = (FEV1/FVC) × 100%; P/F, PaO2/FiO2; MV, mechanical ventilation; NMBA, neuromuscular blocking agent.