Figure 4.

Cardiac functional assessment shows improvement after implantation of bCS-SDF1. (A) The timeline of the experimental procedure. (B) EF (%), (C) FS (%), (D) ESV (μL), and (E) EDV (μL) values measured by echocardiography 5 days post-MI (2 days pre-implant) and 60 days after the implantation of bCS or bCS-SDF1. A group that was operated on but not implanted with bCS was also included as a control. (F) Echocardiographic representative images of the ischemic hearts at diastole and systole. Statistical significance was calculated by ANOVA, with Sidak comparisons between the baseline and the day 60 post-implantation, and is represented as *P < 0.05, **P < 0.01, ***P < 0.001, and ****P < 0.0001. Data were obtained from 7 to 10 animals per group. Mean ± SEM values are represented.