Figure 6.

The histological assessment shows increased heart revascularization after bCS-SDF1 implantation. Representative images of (A) the immunohistochemical staining for lectin+ vessels (brown) and (C) the immunofluorescence staining for SMA+ mature vessels (red) at the peri-infarct zone in treated (bCS-SDF1) and nontreated hearts (control and bCS) at day 60 post-MI. Scale bars: 50 μm (lectin staining), 200 μm (SMA staining). (B) Quantified lectin+ capillaries/mm² and (D) SMA+ arterioles-arteries/mm² at the peri-infarct area of the treated and nontreated hearts. Statistical significance was calculated by ANOVA, with Sidak comparisons between the control and treated groups at day 60 post-implantation, and is represented as *P < 0.05. Data were obtained from 7 to 10 animals per group. Mean ± SEM values are represented.