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. 2023 Nov 10;42:296. doi: 10.1186/s13046-023-02875-y

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — Clinical significance of lncRNA AC016727.1 upregulation in NSCLC tissues and different NSCLC cell subtypes. a Heatmap showing the six lncRNAs pairs upregulated in NSCLC tumor tissues in comparison to paired paracancerous tissues. b Relative expression of lncRNA AC016727.1 in NSCLC and paired paraneoplastic tissues (n = 94). c Relative expression of lncRNA AC016727.1 at different TNM stages in patients with NSCLC. d Kaplan–Meier analysis showing that lncRNA AC016727.1 expression in patients with NSCLC is associated with the overall survival of patients. e Comparing the relative expression of lncRNA AC016727.1 in several NSCLC cell subtypes to that of normal cells (*p < 0.05, **p < 0.01, and ***p < 0.001)