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. 2023 Sep 15;114(11):4459–4474. doi: 10.1111/cas.15942

FIGURE 5.

FIGURE 5

Double staining of CXCL9 and cytokeratin or CD68 by RNAScope and immunohistochemistry in CXCL9‐expressing cases. (A, B) Double staining of CXCL9 mRNA (brown) and cytokeratin (red) using RNAScope and immunohistochemistry in the biopsy sample from Case 11. Yellow arrowheads indicate double‐positive cells. White arrowheads indicate cells positive for CXCL9 but negative for cytokeratin. (C–E). Double staining of CXCL9 mRNA (brown) and CD68 (red), which is a marker for macrophages, in the biopsy samples from cases 11 and 33. Yellow arrowheads indicate CXCL9‐expressing macrophages. White arrowheads indicate cells positive for CXCL9 but negative for CD68 in the biopsy samples from cases 11 and 33. Square area in (E) is shown as (F).