TABLE 2.
Overall mortality outcomes in Wilson's disease patients and reference individuals.
| Wilson's disease | Reference individuals | HR (95%CI) | |||||
|---|---|---|---|---|---|---|---|
| N | Deaths, N (%) | Mortality per 1000 person‐years (95% CI) | N | Deaths, N (%) | Mortality per 1000 person‐years (95% CI) | ||
| All | 151 | 10 (6.6) | 8.53 (4.59–15.85) | 1441 | 31 (2.2) | 2.53 (1.78–3.60) | 3.84 (1.84–8.05) |
| Men | 76 | 5 (6.6) | 8.04 (3.35–19.31) | 728 | 13 (1.8) | 1.99 (1.16–3.43) | 3.53 (1.26–9.92) |
| Women | 75 | 5 (6.7) | 9.09 (3.78–21.84) | 713 | 18 (2.5) | 3.15 (1.98–5.00) | 4.22 (1.46–12.14) |
| Age <20 years at baseline | 50 | 0 (0.0) | 0 | 495 | 2 (0.4) | 0.58 (0.14–2.30) | ‐ |
| Age ≥20 years at baseline | 101 | 10 (9.9) | 11.83 (6.37–22.00) | 946 | 29 (3.1) | 3.31 (2.30–4.76) | 4.17 (1.97–8.82) |
| Wilson's disease, born in Sweden | 102 | 8 (9.4) | 9.80 (4.90–19.60) | 980 | 22 (2.2) | 2.63 (1.73–3.99) | 3.95 (1.73–9.02) |
| Wilson's disease, born outside Sweden | 49 | 2 (4.1) | 5.62 (1.41–22.47) | 461 | 9 (2.0) | 2.33 (1.21–4.48) | 3.47 (0.67–18.00) |
| Neuropsychiatric condition | 50 | 7 (14.0) | 20.72 (9.88–43.47) | 483 | 14 (2.9) | 3.79 (2.25–6.40) | 7.87 (2.85–21.75) |
| No neuropsychiatric condition | 101 | 3 (3.0) | 3.60 (1.16–11.15) | 958 | 17 (1.8) | 1.99 (1.24–3.20) | 1.77 (0.52–6.07) |
Abbreviations: CI, confidence interval; HR, hazard ratio.