TABLE 5.

Cumulative incidence of secondary outcomes in Wilson's disease patients and reference individuals by competing‐risk analysis.

	Wilson's disease patients			Reference individuals
	1 year	5 years	10 years	1 year	5 years	10 years
Liver‐related death	0.8 (0.1–3.9)	‐	‐	0.1 (0.0–0.5)	‐	‐
Liver transplantation	6.6 (3.4–11.3)	7.8 (4.1–13.2)	9.8 (4.9–16.6)	1.0 (0.1–4.8)	1.0 (0.1–4.8)	1.0 (0.1–4.8)
Cardiovascular disease	5.8 (2.5–10.9)	16.1 (9.7–23.8)	25.8 (16.8–35.8)	0.6 (0.3–1.3)	4.3 (3.1–5.8)	9.1 (7.1–11.4)
Atrial fibrillation	0.8 (0.1–3.8)	‐	‐	0.2 (0.1–0.6)	0.5 (0.2–1.1)	1.5 (0.8–2.6)
Non‐hepatic cancer	0.7 (0.1–3.5)	2.6 (0.7–6.9)	‐	0.7 (0.3–1.2)	2.1 (1.4–3.0)	4.8 (3.5–6.4)
Hepatocellular carcinoma	‐	‐	‐	‐	‐	‐
Cholangiocarcinoma	‐	‐	‐	‐	‐	‐
Chronic kidney disease	‐	‐	‐	‐	‐	‐
Psychiatric diagnoses	3.5 (1.1–8.1)	14.3 (8.2–22.2)	23.5 (14.8–33.3)	1.3 (0.7–2.2)	5.9 (4.5–7.6)	12.8 (10.3–15.5)
Neurologic diagnoses	4.8 (2.0–9.6)	11.5 (6.4–18.2)	20.2 (12.4–29.3)	1.1 (0.6–1.8)	5.4 (4.0–6.9)	10.5 (8.4–12.9)
Bone fractures	2.3 (0.6–5.9)	8.7 (4.4–14.7)	19.1 (11.7–27.9)	1.7 (1.1–2.6)	7.8 (6.2–9.7)	13.4 (11.1–15.9)
Parathyroideal disease	‐	‐	‐	‐	‐	‐

Note: Results are in per cent.