12. Results of sensitivity analyses.
Source of bias and No of studies | ||||||
Generation of progestogen | Industry (n=8) | Non‐industry (n=9) | Cohort study (n=8) | Case‐control (n=15) | Objectively confirmed venous thrombosis (n=5) | Subjectively confirmed venous thrombosis (n=11) |
Non‐use | 1 | 1 | 1 | 1 | 1 | 1 |
1st | 2.6 (0.9‐7.4) | 3.3 (2.4‐4.6) | 2.0 (0.4‐10.5) | 3.3 (2.3‐4.7) | 4.5 (3.2‐6.5) | 2.6 (1.3‐5.3) |
2nd | 2.1 (1.0‐4.8) | 3.1 (2.5‐3.8) | 1.7 (0.4‐8.0) | 2.9 (2.3‐3.7) | 3.3 (2.8‐4.0) | 2.5 (1.4‐4.5) |
3rd | 1.9 (0.8‐4.2) | 5.2 (4.2‐6.5) | 2.0 (0.5‐8.6) | 4.2 (3.3‐5.3) | 6.2 (5.2‐7.4) | 3.0 (1.7‐5.4) |
Data are relative risk (95% confidence interval) of venous thrombosis |