Table 1.

Six online plan adaptation methods supported by Unity. SAM = Segment Aperture Morphing

Method	Name	Description
A	Original segments	No modification of segments
B	Adapt segments	Morph segments with SAM
C	Optimize Weights from segments	Method B + segment weight optimization
D	Optimize Weights from fluence	Re-optimize fluence and create new segments + segment weight optimization
E	Optimize Weights and Shapes from segments	Method C + shape optimization
F	Optimize Weights and Shapes from fluence	Method D + shape optimization