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. 2023 Nov 10;102(45):e35344. doi: 10.1097/MD.0000000000035344

Table 3.

Achieving viral suppression following albuvirtide-based dual therapy, by baseline HIV-1 RNA levels (Panel A) and treatment status (Panel B).

A
Duration of treatment Viral Suppression with HIV-1 RNA < 40 copies/mL P value
Group A* N (%, 95%CI) Group B N (%, 95%CI)
2 wk 53 (66.3%, 54.8–76.5%) 28 (39.4%, 28.0–51.8%) .001
4 wk 60 (75.0%, 64.1–84.0%) 35 (49.3%, 37.2–61.4%) .0011
8 wk 72 (90.0%, 81.2–95.6%) 59 (83.1%, 72.3–91.0%) .2118
B
Duration of treatment Viral Suppression with HIV-1 RNA < 40 copies/mL P value
Treatment-naïve patients§ N (%, 95%CI) Treatment-experienced patients N (%, 95%CI)
2 wk 37 (42.5%, 32.0–53.6%) 44 (68.8%, 55.9–79.8%) .0014
4 wk 44 (50.6%, 39.6–61.5%) 51 (79.7%, 67.8–88.7%) .0003
8 wk 72 (82.8%, 73.2–90.0%) 59 (92.2%, 82.7–97.4%) .0912
*

Group A (N = 80): Baseline HIV-1 RNA level <100,000 copies/mL.

Group B (N = 71): Baseline HIV-1 RNA level ≥100,000 copies/mL.

P value of Chi-square test was determined by comparing the percentage difference between groups.

§

Treatment-naïve patients (N = 87).

Treatment-experienced patients (N = 64).