Table 1. Distribution of K13 mutations among different years and sites in the NW region.
K13 genotypes | 2012 | 2013 | 2014 | 2015 | 2016 | Sum | ||||
---|---|---|---|---|---|---|---|---|---|---|
Yingjiang | Tengchong | Ruili | Yingjiang | Yingjiang | Menglian | Yingjiang | Tengchong | Yingjiang | ||
C447S | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
F446I | 9 | 6 | 1 | 35 | 24 | 0 | 1 | 1 | 1 | 79 |
N458Y | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 |
P574L | 2 | 0 | 0 | 4 | 1 | 0 | 0 | 0 | 0 | 7 |
C447R | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
G495C | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
F483S | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
A676D | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 2 |
C580Y | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 |
C469Y | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 2 |
S466I | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Wild | 10 | 18 | 2 | 0 | 2 | 40 | 0 | 0 | 3 | 75 |
Total | 29 | 25 | 5 | 39 | 30 | 40 | 1 | 1 | 4 | 174 |
Note: This isolate showed double K13 mutations of N458Y and F446I. For the convenience of statistics and comparison, it recorded as N458Y.