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. 2023 Oct 26;14:1283722. doi: 10.3389/fendo.2023.1283722

Table 1.

Characteristics of included population based on quartile of dietary carotenoid intake in the NHANES (N =5,056).

Quartile of dietary carotenoid intake (μg/day)
Characteristic Overall,
N = 5056 (100%)
Q1
N = 1265 (25%)
Q2
N = 1263 (25 %)
Q3
N = 1264(25%)
Q4
N = 1264 (25%)
P Value
Age (years) 67.50(67.27,67.73) 67.93(67.45,68.41) 67.25(66.89,67.62) 67.69(67.30,68.08) 67.20(66.79,67.60) 0.04
Gender % <0.01
 Female 52.83 54.36 56.01 53.73 47.79
 Male 47.17 45.64 43.99 46.27 52.21
Ethnicity % <0.01
 Non-Hispanic White 80.35 75.53 80.31 82.32 82.29
 Mexican American 4.11 4.48 3.72 4.68 3.62
 Non-Hispanic Black 7.53 11.28 7.3 5.87 6.38
 Other ethnicities 8.02 8.71 8.67 7.12 7.71
Education % < 0.01
 Grade or less 16.57 22.86 16.83 15.36 12.53
 High school 22.94 28.42 22.41 21.62 20.39
 Some college 31 31.26 33.01 32.92 27.06
 College or more 29.5 17.46 27.75 30.1 40.02
Married status % 66.73 60.37 65.27 68.95 70.98 <0.01
Poverty income ratio 3.20(3.09,3.30) 2.67(2.52,2.82) 3.19(3.06,3.32) 3.34(3.18,3.49) 3.49(3.34,3.64) < 0.01
Smoking status % < 0.01
 Never 12.66 14.49 14.28 11.7 10.63
 Former 40.61 36.36 39.68 43.05 42.49
 Now 12.34 20.02 11.5 10.69 8.65
Drinking status % < 0.01
 Never 12.66 14.49 14.28 11.7 10.63
 Former 22.25 28 24.38 19.83 18.03
 Mild 45.54 36 45.02 47.42 51.73
 Moderate 12.71 12.96 11.29 13.68 12.92
 Heavy 6.84 8.55 5.03 7.37 6.69
Body Mass Index (kg/m2) 29.62(29.31,29.93) 29.85(29.35,30.36) 29.84(29.22,30.46) 29.80(29.33,30.26) 29.07(28.57,29.56) 0.08
Energy intake (kcal/day) 1899.36
(1867.60,1931.12)
1670.82
(1612.52,1729.12)
1836.50
(1769.30,1903.71)
1907.94
(1859.43,1956.45)
2129.89
(2069.76,2190.02)
< 0.01
Physical activity (Yes) % 70.66 63.59 72.36 72.77 72.64 <0.01
Glomerular filtration rate (ml/min/1.73m2) 75.94
(75.12,76.77)
74.81
(73.36,76.25)
75.96
(74.71,77.21)
75.86
(74.30,77.42)
76.90
(75.69,78.11)
0.16
Serum 25-hydroxyvitamin D (nmol/L) 78.31
(76.58,80.05)
74.02
(71.47,76.58)
77.76
(75.04,80.48)
81.04
(78.88,83.21)
79.60
(76.87,82.34)
< 0.01
Systemic immune-inflammation index 553.67
(539.27,568.08)
581.23
(546.18,616.29)
566.62
(535.64,597.61)
551.73
(527.65,575.80)
521.71
(501.85,541.57)
0.01
Use of medication % 85.67 85.33 85.54 87.59 84.23  0.41
S-Klotho level (pg/ml) 815.59
(802.59,828.60)
790.82
(773.13,808.51)
819.91
(797.43,842.39)
814.93
(794.51,835.34)
831.67
(806.78,856.56)
0.06
Total Carotenoid (μg/day) 9775.25
(8971.30,10579.21)
 823.71
(790.56, 856.86)
 3227.55
(3162.43, 3292.68)
 7711.46
(7576.70, 7846.22)
24929.65
(22767.87,27091.44)
< 0.01
 α-Carotene (μg/day) 477.30
(389.28,565.32)
 33.87
(28.19, 39.55)
 159.88
(141.04, 178.73)
 526.14
(481.39, 570.89)
1077.25
(783.97,1370.54)
< 0.01
 β-Carotene (μg/day) 2548.41
(2255.66,2841.16)
 225.47
(210.47, 240.46)
 847.46
(789.32, 905.60)
2329.24
(2207.83,2450.64)
6180.60
(5251.01,7110.19)
< 0.01
 β-Cryptoxanthin (μg/day) 88.40
(80.42,96.39)
 36.67
(31.14, 42.21)
 76.61
( 66.35, 86.86)
 98.34
(81.90,114.79)
130.67
(108.21,153.12)
< 0.01
 Lycopene (μg/day) 4943.17
(4524.48,5361.86)
 136.74
(112.71, 160.78)
 1293.31
(1198.89, 1387.74)
 3378.04
(3194.07, 3562.01)
13642.37
(12444.97,14839.76)
< 0.01
 Lutein with zeaxanthin (μg/day) 1717.97
(1536.96,1898.97)
 390.96
(362.57, 419.34)
 850.29
(787.99, 912.59)
1379.69
(1281.66,1477.73)
3898.76
(3350.39,4447.14)
< 0.01
Self-reported chronic diseases
 CHD % 8.83 9.47 7.81 8.99 9.13 0.73
 Cancer % 23.64 24.13 22.95 24.46 23.11 0.89
 CHF % 5.67 6.26 6.17 6.19 4.25 0.20
 Stroke % 5.87 6.69 7.06 4.1 5.79 0.04
 Heart attack % 7.34 8.26 7.1 7.51 6.68 0.72
 Hypertension % 56.73 59.5 56.12 56.84 55.03 0.51
 Diabetes mellitus % 19.43 18.91 20.29 19.85 18.64 0.34

Continuous variables are described as means ± 95%CI, and categorical variables are presented as percentages. All estimates accounted for complex survey designs. CHF, Congestive heart failure; CHD, Coronary heart disease. Quartile of dietary carotenoid intake (μg/day) with Q1 [0,1745], Q2 (1745,4963.5], Q3 (4963.5,11662.5], Q4 (11662.5,377178].