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Mammalian claudins are mainly divided into two categories. One is classic, and the other is non-classic. The blue dots indicate that the claudin may mostly play a tumor suppressor role in tumors. The red dots indicate that the claudin may mainly play a role in promoting tumors. Yellow dots mean that the claudin plays a tumor-promoting or tumor-suppressing role in different tumors. Green dots indicate that the specific role of claudin in tumors has not been reported yet.
