REAGENT or RESOURCE	SOURCE	IDENTIFIER
Deposited data
The Genotype-Tissue Expression Z score data	Wei Wang and Matthew Stephens, Empirical Bayes Matrix Factorization, 20211	https://github.com/ysfoo/sparsefactor
Genome-scale Perturb-seq experiment data	Joseph Replogle and Jonathan Weissman, Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq, 20222	https://plus.figshare.com/articles/dataset/_Mapping_information-rich_genotype-phenotype_landscapes_with_genome-scale_Perturb-seq_Replogle_et_al_2022_processed_Perturb-seq_datasets/20029387
Software and algorithms
Scikit-learn library: sparse principal component analysis	Python library scikit-learn	https://scikit-learn.org/stable/modules/generated/sklearn.decomposition.SparsePCA.html; RRID:SCR_002577
R Package: Factors and Loadings by Adaptive SHrinkage in R (flashr)	Wei Wang and Matthew Stephens, Empirical Bayes Matrix Factorization1	https://stephenslab.github.io/flashr/index.html
Variational algorithm in SuSiE PCA	This paper	http://www.github.com/mancusolab/susiepca
Python 3.9	Python Software Foundation	https://www.python.org/
R 4.0.0	R Software	https://www.r-project.org
ShinyGO v0.77	Ge SX, Jung D & Yao R3	http://bioinformatics.sdstate.edu/go/; RRID:SCR_019213