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. 2023 Sep 26;31(11):3308–3321. doi: 10.1016/j.ymthe.2023.09.019

Table 3.

VEGF concentrations in serum at different time points after a single subretinal injection of KH631 in bilateral eyes (pg/mL)

Time point (h) 1F001 1M001 1F002 1M002 1F003 1M003
Predose 8.660 14.082 9.706 28.419 5.245 16.674
6 / / / / 1.786 7.853
24 / / / / 1.792 7.942
72 / / / / 5.415 2.279
168 / / / / 1.731 8.009
336 / / / / 0.839 3.999
672 3.337 5.072 / / 0.955 4.915
840 / / / / 1.706 3.554
1008 / / / / 3.530 4.806
1344 / / 7.309 13.937 1.859 11.776
1848 / / / / 2.592 6.548
2184 / / / / 3.235 13.138

“/” means no collected sample and no data.