Table 2.

Associations between cognitive test scores and three module-based PRSs

Cognitive Domain	Cognitive Test	M6			M9			M12
		BETA	SE	P-value	BETA	SE	P-value	BETA	SE	P-value
Executive functioning	TRAASCOR	−0.16	0.12	0.17	0.18	0.06	1.08×10−3	0.02	0.02	0.15
	TRABSCOR	−0.26	0.12	0.03	0.18	0.06	1.58×10−3	0.03	0.02	0.05
Visuospatial functioning	COPYSCORE	0.03	0.12	0.79	−0.12	0.06	0.049	−0.01	0.02	0.77
Language	BNTTOTAL	0.26	0.12	0.03	−0.17	0.06	2.57×10−3	−0.08	0.02	2.23×10−6
	CATAANIMSC	0.29	0.12	0.01	−0.11	0.06	0.05	−0.04	0.02	0.01
Memory	LDELTOTAL	0.22	0.12	0.06	−0.18	0.06	1.14×10−3	−0.07	0.02	4.55×10−5
	LIMMTOTAL	0.18	0.12	0.12	−0.15	0.06	7.18×10−3	−0.08	0.02	4.42×10−6

LIMMTOTAL and LDELTOTAL: logical memory immediate and delayed recall tests; TRAASCOR and TRABSCOR: trail marking test A/B. CATANIMSC: category fluency animal score. BNTTOTAL: Boston naming test total. COPYSCORE: clock test total score

Beta estimates (BETA), standard error (SE), and P-values were calculated with module-based PRSs of the M2, M6, and M9 modules for domain specific cognitive functions.