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. 2023 Jul 22;13(11):4341–4372. doi: 10.1016/j.apsb.2023.07.019

Figure 13.

Figure 13

Various generations of IAP antagonists, 1st generation Smac peptidomimetic antagonist family, 2nd generation Smac peptidomimetic antagonist with bicyclic structure, 3rd generation Smac peptidomimetic antagonist family with bivalent structure, non-peptide IAP antagonists.