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. 2023 May 30;44(6):975–1011. doi: 10.1210/endrev/bnad016

Figure 4.

Figure 4.

The 11β-hydroxysteroid dehydrogenases interconvert active and inactive glucocorticoids (A) and putatively have a critical role in regulating tissue-specific adverse effects that may be limited by 11β-HSD1 inhibition (B).