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. 2014 Mar 6;2014(3):CD005467. doi: 10.1002/14651858.CD005467.pub2

Dai Y 2007.

Methods Country: China
Setting: hospital based
Aim: to observe the therapeutic effect of Migu tablet on BMD, OPG, etc. in patients with postmenopausal osteoporosis
Study design: randomised controlled trial
Analysis: analysis of variance (F‐test)
Loss to follow‐up: not reported
Participants Ethnicity: Chinese
160 postmenopausal osteoporosis patients enrolled: 54 in Migu tablet trial group, 53 in Xianlinggubao group, 53 in compound calcium amino acid chelate capsules group
Inclusion criteria: diagnostic criteria for osteoporosis, BMD detected by DXA
Exclusion criteria: disease‐affected bone metabolism, endocrine diseases, etc
Interventions Experimental: Migu tablet group: Migu tablet, 1 tablet, 3 times a day and compound calcium amino acid chelate capsule, 1 g, once a day; for 24 weeks
Xianlinggubao group: Xianlinggubao capsule, 0.5, g 3 times a day and compound calcium amino acid chelate capsule, 1 g, once a day, for 24 weeks
Control: compound calcium amino acid chelate capsule, 1 g, once a day, for 24 weeks
Outcomes BMD
Notes The study was supported by a health department funded project in Hubei Province, but no declarations of interest for the primary researchers was reported
Risk of bias
Bias Authors' judgement Support for judgement
Adequate sequence generation Low risk Random numbers
Allocation concealment Unclear risk No information provided
Blinding 
 All outcomes Unclear risk Insufficient information to permit judgement of 'low risk' or 'high risk'
Incomplete outcome data addressed 
 All outcomes Low risk No missing outcome data
Free of selective reporting Unclear risk Not all the outcomes that were of interest in this review were reported
Free of other bias Unclear risk No information on baseline comparison