Dai Y 2007.
Methods | Country: China Setting: hospital based Aim: to observe the therapeutic effect of Migu tablet on BMD, OPG, etc. in patients with postmenopausal osteoporosis Study design: randomised controlled trial Analysis: analysis of variance (F‐test) Loss to follow‐up: not reported |
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Participants | Ethnicity: Chinese 160 postmenopausal osteoporosis patients enrolled: 54 in Migu tablet trial group, 53 in Xianlinggubao group, 53 in compound calcium amino acid chelate capsules group Inclusion criteria: diagnostic criteria for osteoporosis, BMD detected by DXA Exclusion criteria: disease‐affected bone metabolism, endocrine diseases, etc |
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Interventions | Experimental: Migu tablet group: Migu tablet, 1 tablet, 3 times a day and compound calcium amino acid chelate capsule, 1 g, once a day; for 24 weeks Xianlinggubao group: Xianlinggubao capsule, 0.5, g 3 times a day and compound calcium amino acid chelate capsule, 1 g, once a day, for 24 weeks Control: compound calcium amino acid chelate capsule, 1 g, once a day, for 24 weeks |
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Outcomes | BMD | |
Notes | The study was supported by a health department funded project in Hubei Province, but no declarations of interest for the primary researchers was reported | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Adequate sequence generation | Low risk | Random numbers |
Allocation concealment | Unclear risk | No information provided |
Blinding All outcomes | Unclear risk | Insufficient information to permit judgement of 'low risk' or 'high risk' |
Incomplete outcome data addressed All outcomes | Low risk | No missing outcome data |
Free of selective reporting | Unclear risk | Not all the outcomes that were of interest in this review were reported |
Free of other bias | Unclear risk | No information on baseline comparison |