Han XL 2007.
Methods | Country: China Setting: outpatients and inpatients Aim: to explore the effect of Shugan Zishen Huoxue tang on postmenopausal osteoporosis Study design: randomised controlled trial Analysis: T‐test, Chi2 test Loss to follow‐up: not reported |
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Participants | Ethnicity: Chinese 42 postmenopausal osteoporosis patients enrolled: 25 in herb trial group, 17 in control group Inclusion criteria: Chinese diagnostic criteria for osteoporosis based on bone density levels, BMD detected by DXA Exclusion criteria: endocrine diseases, etc. |
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Interventions | Experimental: Shugan Zishen Huoxue tang (100 ml, twice a day), Caltrate (1.2 g, twice a day) and alendronate sodium (10 mg, once a day), for 6 months Control: Caltrate (1.2 g, twice a day) and alendronate sodium tablets (10 mg, once a day), for 6 months |
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Outcomes | BMD, E2 | |
Notes | No funding sources or declarations of interest for the primary researchers reported | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Adequate sequence generation | Unclear risk | No information provided |
Allocation concealment | Unclear risk | No information provided |
Blinding All outcomes | Unclear risk | Insufficient information to permit judgement of 'low risk' or 'high risk' |
Incomplete outcome data addressed All outcomes | Low risk | No missing outcome data |
Free of selective reporting | Unclear risk | Not all the outcomes that were of interest in this review were reported |
Free of other bias | Low risk | The study appears to be free of other sources of bias |