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. 2014 Mar 6;2014(3):CD005467. doi: 10.1002/14651858.CD005467.pub2

Han XL 2007.

Methods Country: China
Setting: outpatients and inpatients
Aim: to explore the effect of Shugan Zishen Huoxue tang on postmenopausal osteoporosis
Study design: randomised controlled trial
Analysis: T‐test, Chi2 test
Loss to follow‐up: not reported
Participants Ethnicity: Chinese
42 postmenopausal osteoporosis patients enrolled: 25 in herb trial group, 17 in control group
Inclusion criteria: Chinese diagnostic criteria for osteoporosis based on bone density levels, BMD detected by DXA
Exclusion criteria: endocrine diseases, etc.
Interventions Experimental: Shugan Zishen Huoxue tang (100 ml, twice a day), Caltrate (1.2 g, twice a day) and alendronate sodium (10 mg, once a day), for 6 months
Control: Caltrate (1.2 g, twice a day) and alendronate sodium tablets (10 mg, once a day), for 6 months
Outcomes BMD, E2
Notes No funding sources or declarations of interest for the primary researchers reported
Risk of bias
Bias Authors' judgement Support for judgement
Adequate sequence generation Unclear risk No information provided
Allocation concealment Unclear risk No information provided
Blinding 
 All outcomes Unclear risk Insufficient information to permit judgement of 'low risk' or 'high risk'
Incomplete outcome data addressed 
 All outcomes Low risk No missing outcome data
Free of selective reporting Unclear risk Not all the outcomes that were of interest in this review were reported
Free of other bias Low risk The study appears to be free of other sources of bias