Wu MS 2001.

Methods	Country: China Setting: outpatients and inpatients Aim: to study the effects of Kanggusong granule in the treatment of postmenopausal osteoporosis Study design: randomised controlled trial Analysis: F‐test, T‐test Loss to follow‐up: not reported
Participants	Ethnicity: Chinese 90 postmenopausal osteoporosis patients enrolled: 30 in Kanggusong granule Tieji group, 30 in Kanggusong granule group, 30 in ipriflavone group Inclusion criteria: diagnostic criteria for osteoporosis based on bone density levels, BMD detected by DXA Exclusion criteria: endocrine diseases, etc.
Interventions	Experimental: Kanggusong granule, 12 g, twice a day, for 3 months Control: ipriflavone, 1 tablet, 3 times a day, for 3 months
Outcomes	E2, Ca, P, ALP, PTH
Notes	The study was supported by the National Natural Science Foundation, but no declarations of interest for the primary researchers reported
Risk of bias
Bias	Authors' judgement	Support for judgement
Adequate sequence generation	Unclear risk	No information provided
Allocation concealment	Unclear risk	No information provided
Blinding All outcomes	Unclear risk	Insufficient information to permit judgement of 'low risk' or 'high risk'
Incomplete outcome data addressed All outcomes	Low risk	No missing outcome data
Free of selective reporting	Unclear risk	Not all the outcomes that were of interest in this review were reported
Free of other bias	Unclear risk	No information on baseline