Wu MS 2007.
Methods | Country: China Setting: outpatients and inpatients Aim: to study the effects of prescription for tonifying kidney in the treatment of osteoporosis Study design: randomised controlled trial Analysis: T‐test, Ridit test Loss to follow‐up: not reported |
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Participants | Ethnicity: Chinese 180 osteoporosis patients enrolled: 30 in prescription for tonifying kidney group, 30 in kidney meridian sticking group, 30 in urinary bladder meridian sticking group, 30 in ipriflavone group, 30 in Gushukang group, 30 in non‐meridian or acupoint sticking group Inclusion criteria: Chinese diagnostic criteria for osteoporosis based on bone density levels, BMD detected by DXA Exclusion criteria: secondary osteoporosis, patients with fractures, etc. |
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Interventions | Experimental: prescription for tonifying kidney, 10 pills, 3 times a day; Kanggusong Tieji (kidney meridian sticking or urinary bladder meridian sticking), once per 2 days; for 6 months Control: ipriflavone, 200 mg, 3 times a day, for 6 months |
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Outcomes | BMD, Ca, P, E2, PTH, CT, adverse effects | |
Notes | The study was supported by the National Natural Science Foundation, but no declarations of interest for the primary researchers reported | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Adequate sequence generation | Low risk | Random numbers |
Allocation concealment | Unclear risk | No information provided |
Blinding All outcomes | Unclear risk | Insufficient information to permit judgement of 'low risk' or 'high risk' |
Incomplete outcome data addressed All outcomes | Low risk | No missing outcome data |
Free of selective reporting | Unclear risk | Not all the outcomes that were of interest in this review were reported |
Free of other bias | Low risk | The study appears to be free of other sources of bias |