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. 2014 Mar 6;2014(3):CD005467. doi: 10.1002/14651858.CD005467.pub2

Wu MS 2007.

Methods Country: China
Setting: outpatients and inpatients
Aim: to study the effects of prescription for tonifying kidney in the treatment of osteoporosis
Study design: randomised controlled trial
Analysis: T‐test, Ridit test
Loss to follow‐up: not reported
Participants Ethnicity: Chinese
180 osteoporosis patients enrolled: 30 in prescription for tonifying kidney group, 30 in kidney meridian sticking group, 30 in urinary bladder meridian sticking group, 30 in ipriflavone group, 30 in Gushukang group, 30 in non‐meridian or acupoint sticking group
Inclusion criteria: Chinese diagnostic criteria for osteoporosis based on bone density levels, BMD detected by DXA
Exclusion criteria: secondary osteoporosis, patients with fractures, etc.
Interventions Experimental: prescription for tonifying kidney, 10 pills, 3 times a day; Kanggusong Tieji (kidney meridian sticking or urinary bladder meridian sticking), once per 2 days; for 6 months
Control: ipriflavone, 200 mg, 3 times a day, for 6 months
Outcomes BMD, Ca, P, E2, PTH, CT, adverse effects
Notes The study was supported by the National Natural Science Foundation, but no declarations of interest for the primary researchers reported
Risk of bias
Bias Authors' judgement Support for judgement
Adequate sequence generation Low risk Random numbers
Allocation concealment Unclear risk No information provided
Blinding 
 All outcomes Unclear risk Insufficient information to permit judgement of 'low risk' or 'high risk'
Incomplete outcome data addressed 
 All outcomes Low risk No missing outcome data
Free of selective reporting Unclear risk Not all the outcomes that were of interest in this review were reported
Free of other bias Low risk The study appears to be free of other sources of bias