Xiao W 2008.

Methods	Country: China Setting: hospital based Aim: to study the effects of Gusong decoction in the treatment of osteoporosis Study design: randomised controlled trial Analysis: T‐test Loss to follow‐up: not reported
Participants	Ethnicity: Chinese 40 osteoporosis patients enrolled: 20 in trial group, 20 in control group Inclusion criteria: Chinese diagnostic criteria for osteoporosis based on bone density levels Exclusion criteria: secondary osteoporosis
Interventions	Experimental: Gusong decoction (15 ml, 3 times a day) and alendronate sodium tablet (1 tablet per day), for 5 months Control: alendronate sodium tablet, 1 tablet per day, for 5 months
Outcomes	BMD, E2, ALP, IL‐6, BGP
Notes	No funding sources or declarations of interest for the primary researchers reported
Risk of bias
Bias	Authors' judgement	Support for judgement
Adequate sequence generation	Unclear risk	No information provided
Allocation concealment	Unclear risk	No information provided
Blinding All outcomes	Unclear risk	Insufficient information to permit judgement of 'low risk' or 'high risk'
Incomplete outcome data addressed All outcomes	Low risk	No missing outcome data
Free of selective reporting	Unclear risk	Not all the outcomes that were of interest in this review were reported
Free of other bias	Unclear risk	P value for the baseline comparison not stated