Zhao LN 2003.

Methods	Country: China Setting: hospital based Aim: to observe the effects of Yinyanghuo in the treatment of postmenopausal osteoporosis Study design: double‐blinded, randomised controlled trial Analysis: T‐test Loss to follow‐up: not reported
Participants	Ethnicity: Chinese 25 postmenopausal osteoporosis patients enrolled: 15 in trial group, 10 in control group Inclusion criteria: diagnostic criteria for osteoporosis based on bone density levels, BMD detected by DXA Exclusion criteria: not mentioned
Interventions	Experimental: Yinyanghuo, fried, 200 g per day, 3 times a day, for 3 to 6 months Control: Premarin, 0.625 mg per day, for 3 to 6 months
Outcomes	BMD, Ca, P, ALP
Notes	No funding sources or declarations of interest for the primary researchers reported
Risk of bias
Bias	Authors' judgement	Support for judgement
Adequate sequence generation	Unclear risk	No information provided
Allocation concealment	Unclear risk	No information provided
Blinding All outcomes	Low risk	Double‐blind but did not describe who was blind
Incomplete outcome data addressed All outcomes	Low risk	No missing outcome data
Free of selective reporting	Unclear risk	Not all the outcomes that were of interest in this review were reported
Free of other bias	Unclear risk	No information on baseline