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. 2023 Nov 10;23:1096. doi: 10.1186/s12885-023-11627-2

Table 2.

Treatment, response, and survival status of 10 patients

Case Stagea Gene Mutation Anti-tumor Anti-platelet Tumor response Neurological condition Status OS (mo.)
1 T3N2M0, IIIB EGFR 19DEl Icotinib; Lung radiotherapy Aspirin, Clopidogrel PR Marked Improved Alive 10
2 T1N2M0, IIIA NA No treatment Clopidogrel NA Stable Dead 7
3 T2N1M1, IVA

EGFR

L858R

Gefitinib; Lung radiotherapy Aspirin SD Stable Alive 27
4 T1N1M0, IIIB ALK fusion Ensartinib; Lung radiotherapy Aspirin, Clopidogrel PR Marked Improved Alive 6
5 T1N3M1, IVB

EGFR

L858R

Icotinib; Chemotherapy Clopidogrel PR Marked Improved Alive 17
6 T2N3M0, IIIB NA No treatment Clopidogrel NA Stable Dead 6
7 T1N2Mo, IIIA NA Surgery Aspirin NED Improved Alive 48
8 T2N2M0, IIIA Wild Type Chemotherapy; Surgery Aspirin, Clopidogrel PD Improved Dead 6
9 T2N1M0, IIIB NA No treatment Aspirin, Clopidogrel NA Stable Dead 12
10 T2N2M0, IIIA NA No treatment Clopidogrel NA Stable Dead 7

aAccording to the American Joint Committee on Cancer (8th edition)

Abbreviations: OS Overall survival, EGFR Epidermal growth factor receptor, ALK Anaplastic lymphoma kinase, PR Partial response, SD Stable, PD Progressive disease, NED No evidence of disease, NA Not available