Table 1.
Patients with CDH | |||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Specimen Location | Sex | Race | Death DOL, Days | GA at Birth, wk | Birth Weight, g | o/e TLV, % (Pre→Post FETO) | Liver Herniation, % (Pre→Post FETO) | ECMO | ECMO Duration, Days | FETO | Patch | CDH Side | Ventilation Days | Anomaly | CMA |
RLL | Female | White | 14 | 40 1/7 | 3,079 | 19 →17 | 42 →39 | Yes | 14 | Yes | Yes | Right | 14 | None | Normal |
L Lobe | Female | White | 0 | 36 4/7 | 3,101 | 14→9 | 26→31 | No | Yes | Not repaired | Left | Died within 24 h | None | Normal | |
LUL | Female | White/Asian | 102 | 34 5/7 | 2,070 | 5→ “decreased” | 35→ “Grossly unchanged” | Yes | 18 | Yes | Yes | Bilateral | 102 | Bronchogenic cysts | Normal |
LLL | Female | Black | 22 | 38 5/7 | 2,830 | 21→18 | 34→43 | Yes | 21 | Yes | Yes | Left | 22 | Imperforate anus | Normal |
LLL | Male | White | 4 | 36 6/7 | 2,550 | 16 | 46 | Yes | 4 | No | Yes | Right | 4 | None | Normal |
LUL | Male | White/Hispanic | 24 | 39 3/7 | 3,060 | 15 | 24 | Yes | 13 | No | Yes | Left | 24 | None | Normal |
LLL | Male | White | 48 | 39 4/7 | 3,805 | 28 | 24 | Yes | 35 | No | Yes | Left | 48 | None | N/A |
RLL | Male | White | 48 | 35 0/7 | 2,829 | 18→27 | 61→N/A | Yes | 25 | Yes | Yes | Left | 48 | None | Normal |
Patients with CLM (controls) | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Specimen Location | Sex | Race | GA at Birth | Age at Procedure | Pathology | Procedure | ||||||||
LLL | Female | White | 39 1/7 | 2 mo 27 days | Intralobar sequestration | Open | ||||||||
LLL | Female | White | 36 0/7 | 6 mo 6 days | Intralobar sequestration | VATS | ||||||||
LLL | Female | White | 38 2/7 | 5 mo 7 days | Intralobar sequestration | VATS | ||||||||
LLL | Female | White | 40 0/7 | 6 mo 4 days | Intralobar sequestration | VATS | ||||||||
LLL | Male | White | 39 1/7 | 8 mo | Bronchial atresia | VATS | ||||||||
LLL | Male | White/Hispanic | 40 4/7 | 3 mo 20 days | Bronchial atresia | VATS | ||||||||
LLL | Male | White/Hispanic | 36 3/7 | 3 mo | Intralobar sequestration | VATS | ||||||||
LLL | Male | White/Hispanic | 40 5/7 | 3 mo 16 days | Bronchial atresia | VATS |
CDH, congenital diaphragmatic hernia; CLM, congenital lung malformation; CMA, chromosomal microarray; DOL, day of life; ECMO, extracorporeal membrane oxygenation; FETO, fetoscopic endotracheal occlusion; GA, gestational age; LLL, left lower lobe; N/A, not available; RLL, right lower lobe; TLV, total lung volume; VATS, video-assisted thoracoscopic surgery.