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. 2005 Mar;187(5):1799–1814. doi: 10.1128/JB.187.5.1799-1814.2005

TABLE 2.

Genes downregulated by two different garlic extracts (G1 and G6) and 4-NPO

PA genea Gene Regulation Descriptionb Fold changec
G1 G6 4-NPO
PA0012 Hypothetical protein 1.2 −1.0 −6.8
PA0049 Hypothetical protein −31.7 −12.6 −76.3
PA0059 osmC las + rhl Osmotically inducible protein OsmC −22.2 −23.1 −51.2
PA0063 Hypothetical protein 1.3 1.3 −14.5
PA0105 coxB Cytochrome c oxidase, subunit II −2.3 −1.0 −7.9
PA0106 coxA Cytochrome c oxidase, subunit I −2.1 −1.2 −5.9
PA0107 Conserved hypothetical protein −14.4 −6.2 −23.3
PA0108 colII Cytochrome c oxidase, subunit III −10.3 −4.3 −5.7
PA0112 Hypothetical protein −6.9 −2.1 −15.2
PA0113 Probable cytochrome c oxidase assembly factor −1.7 −1.8 −19.3
PA0119 Probable dicarboxylate transporter −2.8 −1.5 −7.8
PA0121 Hypothetical protein −1.4 −1.3 −5.6
PA0122 las + rhl Conserved hypothetical protein −4.5 −4.5 −14.6
PA0133 Probable transcriptional regulator −1.5 1.4 −14.5
PA0177 Probable purine binding chemotaxis protein −2.7 −3.0 −35.6
PA0187 Hypothetical protein −3.8 −4.1 −16.6
PA0188 Hypothetical protein −28.0 −3.5 −2.4
PA0215 Probable transporter −1.0 1.1 −7.6
PA0216 Probable transporter −1,5 −1.3 −16.4
PA0224 Probable aldolase −1.9 −1.2 −8.5
PA0229 pcaT Dicarboxylic acid transporter PcaT −5.8 −3.1 −1.7
PA0276 Hypothetical protein 0.0 0.0 −7.1
PA0279 Probable transcriptional regulator −2.1 −1.4 −12.7
PA0355 pfpI Protease PfpI −14.2 −8.4 −8.0
PA0397 Probable cation efflux system protein −2.5 −1.5 −10.4
PA0534 Conserved hypothetical protein −3.8 −4.0 −13.2
PA0567 las + rhl Conserved hypothetical protein −21.9 −14.9 −11.4
PA0699 Probable peptidyl-prolyl cis-trans isomerase, PpiC type 0.0 0.0 −11.4
PA0755 Probable porin −2.0 1.3 −5.6
PA0797 Probable transcriptional regulator 2.3 1.1 −9.0
PA0798 pmtA Phospholipid methyltransferase −1.7 −1.3 −15.3
PA0800 Hypothetical protein 0.0 0.0 −35.9
PA0803 Hypothetical protein −2.3 −2.1 −17.2
PA0812 Hypothetical protein −5.1 −1.1 1.2
PA0828 Probable transcriptional regulator −1.8 −1.1 −8.0
PA0846 Probable sulfate uptake protein 1.8 −1.2 −17.3
PA0852 cpbD las + rhl Chitin binding protein CbpD precursor −14.4 −6.2 −16.9
PA0873 phhR Transcriptional regulator PhhR 0.0 0.0 −5.0
PA0887 acsA Acetyl-coenzyme A synthetase 3.6 1.9 −5.4
PA0990 Conserved hypothetical protein −3.5 −5.3 −9.9
PA0996 pqsA las Probable coenzyme A ligase −1.3 1,3 −7.6
PA1111 Hypothetical protein −5.2 −5.0 −6.9
PA1190 Conserved hypothetical protein −2.1 −1.6 −5.2
PA1202 Probable hydrolase −1.9 −1.4 −5.7
PA1216 Hypothetical protein −3.4 −2.2 −13.3
PA1242 Hypothetical protein −6.9 −3.8 −38.9
PA1249 aprA las + rhl Alkaline metalloproteinase precursor −3.4 −5.1 −16.6
PA1255 Hypothetical protein −1.1 −1.6 −9.8
PA1290 Probable transcriptional regulator −1.8 −1.5 −8.6
PA1297 Probable metal transporter −9.8 −8.9 −3.2
PA1298 Conserved hypothetical protein −13.3 −2.7 −2.8
PA1323 las + rhl Hypothetical protein −26.5 −19.5 −32.3
PA1324 las + rhl Hypothetical protein −22.5 −19.1 −21.6
PA1349 Conserved hypothetical protein −1.9 −2.2 −5.4
PA1351 Probable sigma-70 factor, ECF subfamily −1.8 −2.5 −21.7
PA1404 Hypothetical protein −2.7 −3.2 −8.8
PA1412 Hypothetical protein −6.1 −3.7 −3.6
PA1415 Hypothetical protein −2.3 −2.6 −12.6
PA1418 Probable sodium:solute symport protein −3.4 −2.8 −5.2
PA1419 Probable transporter 0.0 0.0 −9.5
PA1421 gbuA Guanidinobutyrase 0.0 0.0 −5.3
PA1470 Probable short-chain dehydrogenase −1.9 −1.6 −5.9
PA1471 Hypothetical protein −6.5 −4.7 −4.4
PA1475 ccmA Heme exporter protein CcmA 1.4 −1.0 −13.0
PA1485 Probable amino acid permease 0.0 0.0 −11.5
PA1486 Hypothetical protein 0.0 0.0 −9.0
PA1514 Conserved hypothetical protein −3.2 −3.4 −15.5
PA1523 xdhB Xanthine dehydrogenase −2.2 −2.2 −24.4
PA1562 acnA Aconitate hydratase 1 −4.3 −3.3 −6.2
PA1617 Probable AMP-binding enzyme −1.6 −2.2 −7.0
PA1651 Probable transporter −1.4 −1.3 −7.8
PA1652 Hypothetical protein −1.2 1.1 −5.7
PA1660 las + rhl Hypothetical protein −8.5 −2.5 −10.6
PA1664 las + rhl Hypothetical protein −8.6 −2.1 −4.6
PA1665 las + rhl Hypothetical protein −5.2 −3.8 −1.8
PA1667 las + rhl Hypothetical protein −5.0 −2.2 −3.4
PA1668 Hypothetical protein −2.7 −1.7 −13.9
PA1669 las + rhl Hypothetical protein −7.7 −2.4 −4.6
PA1670 stp1 Serine/threonine phosphoprotein phosphatase Stp1 −4.9 −3.3 −54.3
PA1700 Conserved hypothetical protein in type III secretion 1.4 1.1 −14.4
PA1730 Conserved hypothetical protein −2.8 −2.6 −5.6
PA1763 Hypothetical protein −1.7 −1.5 −13.7
PA1782 Probable serine/threonine-protein kinase 0.0 0.0 −27.6
PA1784 las Hypothetical protein −5.8 −4.1 −5.2
PA1840 Hypothetical protein 1.4 1.0 −33.2
PA1864 Probable transcriptional regulator −1.7 −2.0 −13.0
PA1866 Hypothetical protein −2.1 −2.1 −36.0
PA1869 las + rhl Probable acyl carrier protein −3.1 −1.8 −8.8
PA1870 Hypothetical protein −7.1 −2.9 −5.7
PA1871 lasA las + rhl Las A protease precursor −12.9 −8.1 −65.2
PA1874 Hypothetical protein −5.5 −8.0 −10.1
PA1875 las Probable outer membrane protein precursor −7.5 −7.5 −45.8
PA1876 Probable ATP binding/permease fusion ABC transporter −4.1 −5.8 −38.3
PA1881 Probable oxidoreductase −2.1 −2.8 −12.6
PA1887 Hypothetical protein −2.2 −6.2 −3.8
PA1888 Hypothetical protein −3.2 −3.4 −5.0
PA1895 Hypothetical protein −1.3 −1.3 −7.9
PA1901 phzC2 rhl Phenazine biosynthesis protein PhzC −7.2 −3.9 −16.1
PA1902 phzD2 rhl Phenazine biosynthesis protein PhzD −7.4 −5.1 −17.4
PA1903 phzE2 rhl Phenazine biosynthesis protein PhzE −10.0 −4.4 −11.5
PA1904 phzF2 rhl Probable phenazine biosynthesis protein −7.5 −5.3 −221.1
PA1905 phzG2 rhl Probable pyridoxamine 5′-phosphate oxidase −8.2 −4.7 −26.2
PA1914 Conserved hypothetical protein −15.8 −11.9 −33.1
PA1921 Hypothetical protein −34.0 −3.0 −18.4
PA1956 Hypothetical protein 0.0 0.0 −8.6
PA1970 Hypothetical protein −2.3 −1.3 −6.4
PA1978 Probable transcriptional regulator 0.0 0.0 −23.7
PA1985 pqqA Pyrroloquinoline quinone biosynthesis protein A −1.8 −2.1 −7.8
PA1988 pqqD Pyrroloquinoline quinone biosynthesis protein D 1.1 −1.6 −11.5
PA1989 pqqE Pyrroloquinoline quinone biosynthesis protein E −1.3 −1.9 −5.3
PA1999 Probable CoA transferase, subunit A 1.1 −2.3 −8.6
PA2000 Probable CoA transferase, subunit B 1.5 −1.7 −8.0
PA2001 atoB Acetyl-CoA acetyltransferase 1.5 −1.9 −9.1
PA2002 Conserved hypothetical protein −2.4 −11.3 −39.5
PA2013 Probable enoyl-CoA hydratase/isomerase −1.2 1.3 −8.6
PA2021 Hypothetical protein −13.0 −10.6 −60.1
PA2030 las + rhl Hypothetical protein −6.8 −4.7 −18.4
PA2031 las + rhl Hypothetical protein −10.8 −4.4 −17.3
PA2035 Probable decarboxylase 0.0 0.0 −27.6
PA2046 Hypothetical protein −47.2 −16.3 −31.2
PA2050 Probable sigma-70 factor, ECF subfamily 2.4 −2.2 −6.7
PA2066 Hypothetical protein −3.9 −5.2 −9.5
PA2067 Probable hydrolase −6.1 −5.7 −6.9
PA2068 rhl Probable MFS transporter −8.8 −5.7 −18.6
PA2069 rhl Probable carbamoyl transferase −24.8 −11.3 −34.1
PA2084 Probable asparagine synthetase 1.5 −3.2 −5.3
PA2086 Probable epoxide hydrolase 1.1 −3.3 −5.1
PA2088 las + rhl Hypothetical protein 0.0 0.0 −12.2
PA2090 Hypothetical protein −1.2 −4.8 −8.2
PA2093 Probable sigma-70 factor, ECF subfamily −1.6 −5.4 −2.0
PA2110 Hypothetical protein −13.4 −15.7 −70.7
PA2111 Hypothetical protein −6.9 −13.6 −14.2
PA2112 Conserved hypothetical protein −18.8 −16.1 −25.5
PA2113 Probable porin −10.8 −6.8 −36.0
PA2114 Probable MFS transporter −73.2 −15.0 −33.5
PA2116 Conserved hypothetical protein −153.1 −62.4 −87.4
PA2134 Hypothetical protein −2.3 −2.4 −29.8
PA2137 Hypothetical protein 0.0 0.0 −33.5
PA2139 Hypothetical protein 0.0 0.0 −5.5
PA2142 Probable short-chain dehydrogenase −8.8 −6.5 −4.1
PA2143 Hypothetical protein −30.8 −8.1 −67.1
PA2144 glgP Glycogen phosphorylase 0.0 0.0 −40.2
PA2146 Conserved hypothetical protein −7.2 −30.9 −24.5
PA2149 Hypothetical protein −4.8 −3.7 −8.3
PA2151 Conserved hypothetical protein −92.9 −78.8 −24.2
PA2153 glgB 1,4 α-Glucan branching enzyme −9.5 −6.6 −26.0
PA2158 Probable alcohol dehydrogenase (Zn dependent) −4.5 −2.7 −17.7
PA2159 Conserved hypothetical protein −1.1 −1.8 −7.9
PA2162 Probable glycosyl hydrolase −2.8 −4.3 −12.4
PA2163 Hypothetical protein −3.1 −4.7 −17.9
PA2165 Probable glycogen synthase −1.5 −2.1 −5.6
PA2166 Hypothetical protein −5.3 −6.3 −10.6
PA2167 Hypothetical protein −12.2 −6.8 −126.9
PA2168 Hypothetical protein −2.5 −4.3 −12.4
PA2169 Hypothetical protein −4.1 −5.9 −3.0
PA2170 Hypothetical protein −9.3 −7.6 −2.1
PA2171 Hypothetical protein −3.0 −2.2 −9.4
PA2172 Hypothetical protein −3.3 −5.5 −3.0
PA2174 Hypothetical protein −3.7 −3.1 −5.9
PA2175 Hypothetical protein −3.2 −3.8 −25.5
PA2176 Hypothetical protein −13.2 −6.5 −143.6
PA2184 Conserved hypothetical protein −3.5 −3.1 −65.9
PA2187 Hypothetical protein −3.2 −1.3 −42.8
PA2190 Conserved hypothetical protein −5.1 −4.6 −18.0
PA2191 exoY Adenylate cyclase ExoY −1.2 −1.1 −5.6
PA2198 Hypothetical protein −1.9 −1.7 −21.2
PA2225 Hypothetical protein −2.2 −1.3 −10.2
PA2226 Hypothetical protein −1.6 −1.8 −5.5
PA2244 Hypothetical protein −3.5 −5.4 −3.3
PA2245 Hypothetical protein −14.1 −3.8 −15.6
PA2250 lpdV Lipoamide dehydrogenase-Val −1.0 1.1 −5.7
PA2251 Hypothetical protein −1.2 1.0 −8.6
PA2272 pbpC Penicillin binding protein 3A 0.0 0.0 −19.9
PA2277 arsR ArsR protein 1.2 −1.0 −12.1
PA2278 arsB ArsB protein −2.0 −1.2 −13.1
PA2296 Hypothetical protein 1.1 −1.6 −10.1
PA2300 chiC rhl Chitinase −37.1 −20.5 −32.4
PA2317 Probable oxidoreductase −1.3 −1.4 −10.6
PA2322 Gluconate permease −2.9 −2.4 −49.5
PA2414 las + rhl l-sorbosone dehydrogenase −14.8 −8.7 −7.0
PA2415 las + rhl Hypothetical protein −13.2 −5.7 −9.4
PA2433 las + rhl Hypothetical protein −41.8 −28.9 −30.8
PA2448 Hypothetical protein −3.5 −3.3 −35.8
PA2457 Hypothetical protein −1.4 −1.3 −9.8
PA2485 Hypothetical protein −8.9 −10.4 −6.8
PA2486 Hypothetical protein −6.9 −6.4 −5.0
PA2505 Probable porin −1.5 −1.2 −8.1
PA2528 Probable RND efflux membrane fusion protein precursor −1.1 −1.5 −5.3
PA2534 Probable transcriptional regulator −1.4 −1.7 −6.3
PA2557 Probable AMP binding enzyme −9.0 −6.6 −6.9
PA2564 las + rhl Hypothetical protein −2.5 −18.8 −1.9
PA2570 palL rhl PA-I galactophilic lectin −50.6 −16.9 −19.0
PA2598 Hypothetical protein 2.9 −1.8 −20.7
PA2602 Hypothetical protein 1.5 −1.2 −10.8
PA2692 Probable transcriptional regulator −2.2 1.3 −5.3
PA2696 Probable transcriptional regulator −1.5 −1.1 −10.4
PA2698 Probable hydrolase −1.5 −1.1 −12.6
PA2701 Probable MFS transporter 1.2 −1.9 −6.2
PA2708 Hypothetical protein −2.3 −3.4 −98.8
PA2717 cpo Chloroperoxidase precursor −4.2 −4.9 −39.8
PA2722 Hypothetical protein −2.7 −2.2 −7.9
PA2746 Hypothetical protein −4.2 −2.7 −18.6
PA2747 las + rhl Hypothetical protein −18.8 −16.6 −11.5
PA2751 Conserved hypothetical protein −5.0 −3.4 −10.8
PA2754 Conserved hypothetical protein −10.7 −8.9 −4.8
PA2777 Conserved hypothetical protein −6.7 −6.9 −14.1
PA2819 Hypothetical protein −0.0 0.0 −5.2
PA2862 lipA Lactonizing lipase precursor −1.4 −1.6 −6.3
PA2893 Probable very-long-chain acyl-CoA synthetase −1.6 −1.2 −5.8
PA2895 Hypothetical protein −2.3 −3.8 −11.1
PA2909 Hypothetical protein 1.0 −1.3 −11.1
PA2937 Hypothetical protein −3.8 −3.9 −13.7
PA2939 las Probable aminopeptidase −4.7 −3.2 −38.9
PA3019 Probable ATP binding component of ABC transporter 1.2 −1.2 −6.8
PA3025 Probable FAD dependent glycerol-3-phosphate dehydrogenase −1.5 −1.1 −8.0
PA3042 Hypothetical protein −1.8 −4.0 −8.2
PA3181 2-Keto-3-deoxy-6-phosphogluconate aldolase −1.4 −1.6 −8.8
PA3183 zwf Glucose-6-phosphate 1-dehydrogenase −2.2 −3.2 −5.1
PA3231 Hypothetical protein −11.8 −12.0 −24.7
PA3234 Probable sodium:solute symporter −13.2 −13.9 −5.3
PA3235 Conserved hypothetical protein 0.0 0.0 −13.4
PA3250 Hypothetical protein −1.7 −1.7 −6.2
PA3251 Hypothetical protein −2.4 −2.3 −6.0
PA3271 Probable two-component sensor −1.3 −1.6 −21.5
PA3273 Hypothetical protein −4.5 −5.9 −14.4
PA3274 las + rhl Hypothetical protein −15.6 −7.3 −58.6
PA3316 Probable permease of ABC transporter −1.7 −1.2 −12.5
PA3324 Probable short-chain dehydrogenase 0.0 0.0 −9.9
PA3332 rhl Conserved hypothetical protein −1.7 1.6 −5.7
PA3333 fabH2 rhl 3-Oxoacyl-[acyl-carrier-protein] synthase III −1.5 1.3 −10.5
PA3336 rhl Probable MFS transporter −1.7 1.5 −6.7
PA3361 rhl Hypothetical protein −8.7 −7.0 −46.9
PA3365 Probable chaperone 0.0 0.0 −18.0
PA3366 amiE Aliphatic amidase −1.7 −2.0 −6.8
PA3369 Hypothetical protein −5.4 −6.4 −41.8
PA3370 Hypothetical protein −10.1 −12.3 −23.7
PA3371 las + rhl Hypothetical protein −9.8 −9.5 −84.9
PA3416 Probable pyruvate dehydrogenase E1 component, beta chain −4.1 −6.3 −5.8
PA3451 Hypothetical protein −2.7 −3.7 −9.1
PA3459 Probable glutamine amidotransferase −9.7 −5.3 −4.3
PA3460 Probable acetyltransferase −9.9 −5.7 −14.0
PA3461 Conserved hypothetical protein −6.0 −7.3 −8.6
PA3466 Probable ATP-dependent RNA helicase 1.1 1.1 −7.9
PA3478 rhlB las + rhl Rhamnosyltransferase chain B −10.5 −7.1 −44.0
PA3479 rhlA las + rhl Rhamnosyltransferase chain A −9.6 −7.2 −29.1
PA3492 Conserved hypothetical protein −3.0 −1.7 −5.5
PA3500 Conserved hypothetical protein −1.8 −1.8 −7.6
PA3520 las + rhl Hypothetical protein −8.5 −9.1 −87.3
PA3562 Probable phosphotransferase system enzyme I −1.7 −1.8 −13.2
PA3581 glpF Glycerol uptake facilitator protein 0.0 0.0 −76.5
PA3584 glpD Glycerol-3-phosphate dehydrogenase −1.9 −1.4 −9.2
PA3691 las + rhl Hypothetical protein −13.4 −9.4 −12.8
PA3692 las + rhl Probable outer-membrane protein precursor −22.3 −14.2 −14.0
PA3706 Probable protein methyltransferase −1.4 −1.7 −5.3
PA3710 Probable GMC-type oxidoreductase 0.0 0.0 −10.2
PA3724 lasB las + rhl Elastase LasB −6.8 −3.1 −22.6
PA3734 Hypothetical protein −7.3 −5.0 −32.9
PA3739 Probable sodium/hydrogen antiporter −1.5 −1.4 −22.3
PA3758 Probable N-acetylglucosamine-6-phosphate deacetylase −3.1 −2.1 −6.0
PA3779 Hypothetical protein −1.7 −2.0 −5.1
PA3788 Hypothetical protein −8.4 −7.6 −6.5
PA3815 Conserved hypothetical protein −2.1 −2.1 −9.8
PA3819 Conserved hypothetical protein −5.2 −5.3 −3.1
PA3845 Probable transcriptional regulator −1.7 −1.6 −17.1
PA3887 nhaP Na+/H+ antiporter NhaP 1.0 1.1 −17.2
PA3888 Probable permease of ABC transporter −7.1 −8.6 −8.7
PA3889 Probable binding protein component of ABC transporter −4.8 −6.7 −10.5
PA3890 las + rhl Probable permease of ABC transporter −5.6 −5.7 −95.6
PA3898 Probable transcriptional regulator 1.2 −1.4 −18.3
PA3920 Probable metal transporting P-type ATPase −1.3 −1.8 −28.4
PA3923 Hypothetical protein −1.6 −1.0 −9.0
PA3957 Probable short-chain dehydrogenase −3.6 −1.8 −5.9
PA4078 Probable nonribosomal peptide synthetase −7.2 −5.2 −8.0
PA4086 cupB1 Probable fimbrial subunit CupB1 −1.6 1.1 −11.2
PA4106 Conserved hypothetical protein −1.7 −1.1 −5.5
PA4129 las + rhl Hypothetical protein −2.6 −6.5 −7.2
PA4130 las + rhl Probable sulfite or nitrite reductase −2.1 −8.3 −13.2
PA4133 las + rhl Cytochrome c oxidase subunit (cbb3 type) −5.6 −11.5 −123.5
PA4134 las + rhl Hypothetical protein −3.4 −3.5 −5.4
PA4138 tyrS Tyrosyl-tRNA synthetase 0.0 0.0 −11.7
PA4141 las + rhl Hypothetical protein −6.6 −4.4 −23.7
PA4142 las + rhl Probable secretion protein −7.2 −5.6 −33.9
PA4143 Probable toxin transporter −4.7 −3.5 −148.3
PA4171 Probable protease −4.7 −2.5 −16.8
PA4172 Probable nuclease −6.4 −3.4 −7.0
PA4175 prpL las Pvds-regulated endoprotease, lysyl class −6.9 −4.2 −20.7
PA4199 Probable acyl-CoA dehydrogenase −1.7 −1.2 −9.2
PA4204 Conserved hypothetical protein −7.6 −3.2 −4.5
PA4205 mexG Hypothetical protein −4.1 −3.7 −6.0
PA4207 mexl Probable RND efflux transporter −4.1 −5.3 −3.3
PA4209 phzM rhl Probable phenazine-specific methyltransferase −4.2 −3.1 −17.1
PA4210 phzA1 rhl Probable phenazine biosynthesis protein −5.6 −2.7 −15.17
PA4211 phzB1 rhl Probable phenazine biosynthesis protein −6.4 −3.5 −25.0
PA4217 phzS rhl Flavin-containing monooxygenase −5.3 −2.7 −15.4
PA4290 Probable chemotaxis transducer −4.4 −8.1 −27.1
PA4294 Hypothetical protein −2.0 −2.7 −5.5
PA4300 Hypothetical protein −2.8 −3.5 −5.7
PA4302 Probable type II secretion system protein −3.6 −8.5 −3.2
PA4303 Hypothetical protein −2.5 −6.0 −6.0
PA4304 Probable type II secretion system protein −2.6 −3.5 −5.2
PA4305 Hypothetical protein −3.4 −4.3 −21.1
PA4306 las + rhl Hypothetical protein −5.7 −10.1 −20.1
PA4342 Probable amidase 1.0 −1.0 −25.8
PA4345 Hypothetical protein −4.9 −5.7 −10.8
PA4346 Hypothetical protein −1.4 −2.3 −9.0
PA4354 Conserved hypothetical protein −1.7 −1.4 −28.4
PA4377 Hypothetical protein −4.7 −6.1 −15.9
PA4391 Hypothetical protein −1.5 −1.6 −7.1
PA4397 panE Ketopantoate reductase −1.4 −1.5 −6.1
PA4435 Probable acyl-CoA dehydrogenase −1.0 1.4 −5.4
PA4456 Probable ATP-binding component of ABC transporter 1.5 1.3 −5.9
PA4573 Hypothetical protein −4.1 −5.6 −4.4
PA4648 Hypothetical protein −5.2 −8.8 −11.9
PA4649 Hypothetical protein −3.7 −8.7 −20.9
PA4650 Hypothetical protein −5.4 −4.3 −31.2
PA4651 Probable pilus assembly chaperone −3.4 −5.7 −4.3
PA4653 Hypothetical protein −2.0 −1.8 −8.5
PA4738 las + rhl Conserved hypothetical protein −5.4 −7.2 −76.7
PA4739 las + rhl Conserved hypothetical protein −11.4 −11.3 −28.1
PA4785 Probable acyl-CoA thiolase −4.8 −4.5 −10.1
PA4786 Probable short-chain dehydrogenase −3.2 −3.3 −12.0
PA4788 Hypothetical protein −1.7 −1.7 −13.9
PA4816 Hypothetical protein −4.1 −1.8 −11.4
PA4828 Conserved hypothetical protein −1.3 1.1 −8.6
PA4829 lpd3 Dihydrolipoamide dehydrogenase 3 −1.3 −1.7 −14.3
PA4835 Hypothetical protein −11.9 −2.3 −2.1
PA4869 Hypothetical protein −2.5 −2.2 −15.9
PA4876 osmE Osmotically inducible lipoprotein OsmE −13.5 −12.9 −10.2
PA4877 Hypothetical protein −4.0 −5.7 −3.9
PA4880 Probable bacterioferritin −3.7 −4.2 −14.2
PA4908 Hypothetical protein 0.0 0.0 −8.4
PA4910 Probable ATP-binding component of ABC transporter −1.5 −1.2 −18.7
PA4980 Probable enoyl-CoA hydratase/isomerase 1.0 −1.0 −14.4
PA5034 hemE Uroporphyrinogen decarboxylase 0.0 0.0 −6.1
PA5061 Conserved hypothetical protein −4.1 −3.7 −7.2
PA5093 Probable histidine/phenylalanine ammonia-lyase 0.0 0.0 −5.5
PA5096 Probable binding protein component of ABC transporter 0.0 0.0 −12.8
PA5098 hutH Histidine ammonia-lyase −2.9 −6.6 −2.6
PA5099 Probable transporter 0.0 0.0 −21.9
PA5100 hutU Urocanase 1.6 −3.2 −5.2
PA5155 Probable permease of ABC transporter 1.0 1.5 −8.3
PA5171 arcA Arginine deiminase −5.7 −2.6 1.5
PA5172 arcB Omithine carbamoyltransferase, catabolic −6.4 −2.7 1.4
PA5173 arcC Carbamate kinase −7.6 −4.5 −1.3
PA5212 Hypothetical protein −8.4 −8.7 −5.8
PA5235 glpT Glycerol-3-phosphate transporter −5.7 −2.1 −13.3
PA5297 paxB Pyruvate dehydrogenase (cytochrome) −4.7 −3.7 −6.6
PA5352 Conserved hypothetical protein −1.3 −1.3 −5.1
PA5383 Conserved hypothetical protein −5.7 −3.1 −5.9
PA5457 Hypothetical protein 1.0 1.0 −17.0
PA5460 Hypothetical protein −6.8 −2.8 −2.0
PA5468 Probable citrate transporter −1.9 1.2 −6.7
PA5481 las + rhl Hypothetical protein −5.8 −12.2 −79.3
PA5482 las + rhl Hypothetical protein −22.7 −16.6 −77.0
PA5503 Probable ATP binding component of ABC transporter 1.8 −1.9 −5.4
PA5506 Hypothetical protein −5.0 −3.1 −4.5
PA5517 Conserved hypothetical protein −1.1 −1.1 −13.6
PA5541 Probable dihydroorotase −2.4 −1.1 −11.6
PA5544 Conserved hypothetical protein −5.5 −2.5 −1.3
a

Genes marked with boldface type were found to be QS regulated (25).

b

Description from the Pseudomonas genome project (http://www.pseudomonas.com). CoA, coenzyme A; MFS, major facilitator superfamily.

c

Values are fold change in hybridization signal comparing a treated and untreated planktonic culture at OD600 = 2.0. Boldface type indicates a change of fivefold or higher. LasR/RhlR regulation is defined by Hentzer et al. (25).