Table 1.
Studies characteristics and results summary
| Author-year | Design | Sample (N) | % of H/L | Treatment phase | Stage | Mean Age (yr) | Mean BMI (kg*m−2) | PA levels | Intervention type | Study length (weeks) | Freq. (n/w) | Intensity (%) | Results CVD-related outcomes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greenlee et al. 2012 | RCT | 38 | 79 | >6 months post-treatment | 0–IIIa | 50.7±68.9 | 33.2±5.9 | Sedentary | COMB (circuit) | 24 | 3 | <60% – 70–75% of HRmax (AT) |
No changes in cardiorespiratory fitness (VO2max). Significant weight loss in IG vs CG (no significant diff. by ethnicity). No changes in metabolic biomarkers (cholesterol, TGs, glucose, hsCRP, insulin, total ghrelin, adiponectin, IGF, HOMA-IR) |
| Hughes et al. 2008 | Single arm | 25 | 100 | >6 months post-treatment | I–IV | 50±8.4 | n/a | n/a | COMB | 10 | n/a | n/a | Significant increase in cardiorespiratory fitness (VO2max) |
| Lee et al. 2019 | RCT | 30 | 73 | On chemotherapy | I–III | 46.9±9.8 | 31.0±7.5 | <30 min of PA/week | HIIT | 8 | 3 | 10%/90% PPO (60rpm) |
IG increased in PPO and VO2max, while CG significantly decreased both PPO and VO2max. No time×group interaction. |
| Lee et al. 2021 | Cardiorespiratory fitness (6MWT) significantly increased in IG vs CG. | ||||||||||||
| Ortiz et al. 2021 | RCT | 89 | 100 | >3 months post-treatment | I–IV | 55.4±10 | 31±6.5 | Not active (ACSM definition) | COMB | 16 | 2 | n/a |
Cardiorespiratory fitness (6MWT) increased in IG, without significant differences between IG and CG. |
| Owens et al. 2009 | Quasi-experimental | 13 | 100 | During and after chemotherapy | I–II | 51.5# | n/a | Not exercising | COMB | 24 | 3 | n/a | No significant changes in weight, BMI, % body fat, and fasting glucose. |
ACSM American College of Sports Medicine, BMI body mass index, CG control group, COMB combined aerobic and resistance exercise, Freq. frequency, F-U follow-up, H/L Hispanic/Latina, HIIT high intensity interval training, HOMA-IR homeostasis model assessment-estimated insulin resistance, HRmax maximum heart rate, IG intervention group, IGF insulin-like growth factor, n/a not available, PA physical activity, PF physical fitness, PPO peak power output, RCT randomized controlled trial, VO2max maximal oxygen consumption
#calculated based on age range.