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. 2023 Nov 11;14:7301. doi: 10.1038/s41467-023-42900-4

Table 3.

PFS for patients receiving dostarlimab + chemotherapy and pembrolizumab + chemotherapy (ITT population as of August 4, 2022)

Variable Dostarlimab + chemotherapy (N = 121) Pembrolizumab + chemotherapy (N = 122)
Median PFS follow-up time, months (IQR) 9.1 (6.8–11.4) 9.0 (6.7–11.2)
PFS events observed, n 64 74
Median PFS (95% CI), months 8.8 (6.7–10.4) 6.7 (4.9–7.1)
Estimated probability of PFS, % (95% CI)
  6 months 61 (52–70) 52 (42–61)
  9 months 46 (36–56) 36 (26–45)
Hazard ratio (95% CI) 0.70 (0.50–0.98)

PFS was assessed per RECIST v1.1 based on investigator assessment.

CI confidence interval, IQR interquartile range, ITT intention-to-treat, PFS progression-free survival, RECIST v1.1 Response Evaluation Criteria in Solid Tumors version 1.1.