Table 5.
Association between parental carrier status of the variant allele(s) and breast cancer risk in daughters
Test statistic | ||||
Mothers' carrier status and disease risk in daughters | Fathers' carrier status and disease risk in daughters | |||
Variant allele(s) | Additive | Dominant | Additive | Dominant |
CYP17 | ||||
C | 1.47 | 1.09 | 1.40 | 1.07 |
P | 0.07 | 0.14 | 0.08 | 0.14 |
CYP19 | ||||
(TTTA)≥10 | 1.73 | 1.65 | 0.95 | 0.45 |
P | 0.04 | 0.05 | 0.17 | 0.33 |
(TTTA)11 | 1.52 | 1.96 | - 0.11 | 0.18 |
P | 0.06 | 0.03 | 0.46 | 0.43 |
The test statistic was calculated under the additive model. P values are based on one-tailed test statistics.