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. 2023 Sep 9;7(21):6589–6598. doi: 10.1182/bloodadvances.2023010624

Table 4.

Risk factors of NRM at lymphodepletion by multivariate analysis

Parameter Odds ratio estimate Lower 95% CI limit for odds ratio Upper 95% CI limit for odds ratio
Age, y, ≥65, yes vs no 1.033 0.992 1.075
Diabetes, yes vs no 4.417 1.651 11.819
ECOG PS of ≥2 at lymphodepletion, yes vs no 2.354 0.607 9.126
Platelets < 50 G/L at lymphodepletion, yes vs no 1.133 0.446 2.878
Elevated ferritin level at lymphodepletion, yes vs no 2.716 1.003 7.350
C-reactive protein level > 30 mg/L at lymphodepletion, yes vs no 1.246 0.399 3.892

Logistic regression for the prediction of NRM comparing the overall NRM population with patients alive without progression at 1 year after CAR T-cell infusion.