Table 2.
Relation of Q356R and breast cancer risk in the Nurses' Health Study
Genotype | Case (frequency)a | Control (frequency)a | OR (95% CI) | ORb (95% CI) |
Q356Q | 1065 (86.23) | 1413 (87.01) | 1.00 (reference) | 1.00 (reference) |
Q356R | 165 (13.36) | 206 (12.68) | 1.06 (0.85–1.32) | 1.05 (0.84–1.32) |
R356R | 5 (0.4) | 5 (0.31) | 1.33 (0.38–4.59) | 1.67 (0.44–6.35) |
CI, confidence interval; OR, odds ratio.
aSamples lacking genotype information were removed from analysis.
bLogistic regression controlling for age, age of menopause, post-menopausal hormone use, age at first birth, parity, family history of breast cancer, and history of benign breast disease.