FIG. 1.
Metabolic pathways potentially involved in the synthesis of glutamic acid from the glycolytic intermediates. Thin arrows, enzymes not assayed in this study; thick arrows, enzymes detected in L. lactis NCDO 2118; dashed arrows, enzymes not detected in L. lactis NCDO 2118; 1, enzyme not detected but considered to be present. Abbreviations: OAA, oxaloacetic acid; αKG, α-ketoglutaric acid; Glu, glutamic acid; Gln, glutamine; PEPC, PEP carboxylase; PC, pyruvate carboxylase; ME, malic enzyme; CS, citrate synthase; AK, aconitase; IDH, isocitrate dehydrogenase; KGDH, α-ketoglutarate dehydrogenase; IL, isocitrate lyase; MS, malate synthase; GDH, glutamate dehydrogenase; T, transaminase (or aminotransferase); GS, glutamine synthetase; Gase, glutaminase.