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Fucoxanthin inhibited TBI-induced endothelial cell oxidative damage
(A and B) MDA levels (A) and Gpx activity (B) were evaluated by ELISA at 3 days after TBI and fucoxanthin i.c.v. injection.
(C) Representative images of IF staining for 8-OHdG+ and CD31+ cells at 3 days after TBI and fucoxanthin i.c.v. injection. n = 3 per group.
Data were presented as mean ± SD; ∗∗∗p < 0.001 versus sham group; ##p < 0.01, ###p < 0.001 versus TBI + vehicle group. Scale bar: 20 μm.
