Table 2.
Absolute values of remodeling markers in the airway and alveolar septa.
| OXIDATIVE STRESS MARKERS | SAL | OVA | OVA ANTI-IL-17 | PPE | PPE ANTI-IL-17 | ACO | ACO ANTI-IL-17 |
|---|---|---|---|---|---|---|---|
| 8-iso-PGF-2α (%) Airway | 0.19 ± 0.06 | 5.49 ± 1.36* | 0.53 ± 0.12& | 1.70 ± 0.89 | 0.86 ± 0.26 | 8.27 ± 2.38*+ | 4.56 ± 1.08& |
| 8-iso-PGF-2α(%) Alveolar Septa | 0.42 ± 0.02 | 2.20 ± 1.03* | 1.67 ± 0.16 | 2.19 ± 0.42* | 0.51 ± 0.01& | 2.64 ± 0.61* | 0.92 ± 0.04& |
| iNOS (Positive Cells/104µm2) Airway | 4.07 ± 0.74 | 30.01 ± 1.81 | 15.37 ± 1.45& | 23.11 ± 0.56* | 11.670 ± 1.10& | 25.12 ± 2.35* | 12.91 ± 1.21& |
| iNOS (Positive Cells/104µm2) Alveolar Septa | 11.49 ± 2.72 | 18.44 ± 0.94* | 12.05 ± 1.33& | 21.47 ± 3.23* | 13.75 ± 0.74& | 26.71 ± 2.07*# | 20.18 ± 2.83& |
| Nitric Oxide Exhaled (pph) | 5.30 ± 2.49 | 24.17 ± 4.30* | 9.75 ± 1.14& | 9.61 ± 2.19 | 8.74 ± 1.23 | 13.73 ± 4.42* | 9.42 ± 2.50 |
Oxidative stress for 8-iso-PGF-2α, iNOS in airway and alveolar septa and Nitric oxide exladed. Mean ± standard error of Oxidative stress assessment for all experimental groups. Values are presented as absolutes. *p < 0.05, compared to the SAL group; + p < 0.05 comparado ao grupo PPE; # p < 0.05 comparado ao grupo OVA; &p < 0.05, compared to the OVA, PPE, and ACO groups.