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. 2023 Oct 4;299(11):105319. doi: 10.1016/j.jbc.2023.105319

Figure 7.

Figure 7

PrP KO alters NSC cellular metabolic profile. Web diagram of affected metabolite pools in energy producing metabolism associated with the loss of PrP in NSCs. Coloring of each node indicates the base 2 logarithm of the fold change of the PrP KO versus the WT while size reflects the negative logarithm of the p-value from an unpaired t test. Positions of glycolysis, the pentose phosphate pathway, and tricarboxylic acid (TCA) cycle are indicated. n = 6. Explanation of abbreviations can be found in Table 2. NSC, neural stem cell; PrP, prion protein.