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. 2023 Oct 27;14:1287656. doi: 10.3389/fimmu.2023.1287656

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Copyright © 2023 Tamassia, Bianchetto-Aguilera, Gasperini, Grimaldi, Montaldo, Calzetti, Gardiman, Signoretto, Castellucci, Barnaba, Tripodi and Cassatella

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Characterization of monocyte clusters identified by scRNA-seq analysis. (A) Dot plot showing the top 10 genes, sorted by average log fold change, specific for the monocyte clusters (c1-c6) as identified and shown in Figure 4C . Dot size represents the percentage of cells in each cluster with more than one read of the corresponding gene. The color intensity of the dots represents the level of expression of the genes. (B) Violin plots showing the mRNA expression levels (as ln(UMI)) of selected genes (i.e., IRF8, KLF4, CEACAM8, S100P, CEBPE and CD34) across c1-c6 cells.