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. Author manuscript; available in PMC: 2024 Aug 24.
Published in final edited form as: J Med Chem. 2023 Aug 8;66(16):11250–11270. doi: 10.1021/acs.jmedchem.3c00671

Figure 1.

Figure 1.

(A) Composition of the three BAF subcomplexes. In dark gray: catalytic subunit; in light gray: subunits shared by all complexes; in yellow: subunits shared by cBAF and PBAF; in purple: subunits shared by BAF and GBAF; in red: cBAF unique subunits; in green: PBAF unique subunits; in blue: GBAF unique subunits. Bromodomain-containing proteins are labeled in underlined white bold font. (B) Phylogenetic BD tree as described by Filippakopoulos et al.28 (C) Reported BRD7/9 ligands with selectivity for BRD9 over BRD7.