Delta protocadherin expression in the epithelium
(A–D) Pcdh19 and Pcdh1 were assessed for expression at E17 (A and B) and in adulthood (C and D). (A) Pcdh1 is spatially differentially expressed in E17 epithelia, with notable enrichment in certain regions of the epithelium (e.g., black arrow).
(B) Pcdh19 is expressed in a distinctly different pattern from Pcdh1, with weaker expression dorsolaterally (black arrow; compare (A) and (B)), and stronger expression medially (boxed region).
(C and D) Adult epithelial expression of Pcdh1 (C) and Pcdh19 (D). Only a portion of the dorsolateral epithelium is shown (black arrows), corresponding to the analogous region indicated with black arrows in (A) and (B). Scale bar:25 μm.