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. 2023 Oct 18;30(1):302–314. doi: 10.1159/000534669

Fig. 4.

Fig. 4.

Effect of STZ administration and UCMS protocol on mRNA expression in hippocampus and frontal cortex. a STZ increased hippocampal expression of Tnf and Bdnf compared to buffer mice. b STZ increased frontal cortex expression of Il1b compared to buffer mice while UCMS decreased frontal cortex expression of Il1b compared to control mice. Data are graphed as means ± SEM; *p < 0.05. #p < 0.05 stress effect. n = 4–7 mice per group. UCMS, unpredictable chronic mild stress; STZ, streptozotocin; SEM, standard error of the mean.