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. 2023 Oct 27;10:1258395. doi: 10.3389/fmed.2023.1258395

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Copyright © 2023 Pérez-Jeldres, Magne, Ascui, Alvares, Orellana, Alvarez-Lobos, Hernandez-Rocha, Azocar, Aguilar, Espino, Estela, Escobar, Zazueta, Baez, Silva, De La Vega, Arriagada, Pavez-Ovalle, Díaz-Asencio, Travisany, Miquel, Villablanca, Kronenberg and Bustamante.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Genetic principal component analyses of study individuals and Mapuche, European, African, and Aymara reference individuals. This figure shows the distribution of ancestry informative markers (ATMs) in the sample. PC1 distinguished Native American and European from Africans. The PC2 separated Native American from European ancestry components. CD and UC patients revealed greater European and Mapuche ancestry influences in our study population. The PC3 distinguished Mapuche from European and Aymara. Crosses represent reference populations, orange = Mapuche, blue = Aymara, green = European, yellow = African. Dark blue dots represent Ulcerative Colitis patients, and red dots Crohn's disease patients. PC = Principal Component.