Table 5.

Multivariable logistic regression analysis for AKI and multivariable linear regression analysis for the absolute change in creatinine

Variable	Parameter estimate	Standard error	P value
Multivariable logistic regression analysis for AKI∗
Lower preoperative creatinine (per mg/dL)	−0.048	0.015	<0.001
Longer total duration of CPB (per 10 min)	0.109	0.027	<0.001
Multivariable linear regression analysis for absolute change in creatinine†
Higher preoperative AST level (per 10 U/mL)	0.32	0.03	<0.001
Longer total duration of CPB (per 10 min)	0.87	0.23	<0.001
Catheter reintervention	23.3	7.8	0.004
ECMO	27.2	7.4	<0.001

AKI, acute kidney injury; AST, aspartate transaminase; CPB, cardiopulmonary bypass; ECMO, extracorporeal membrane oxygenation.

Not including repeated measures of inflammatory and vascular markers and microparticles.

^∗Model c-statistic = 0.78.

^†Adjusted model R²= 0.52; note that preoperative creatinine was not significant in this model.