Table 3.
Subgroup analyses in terms of overall survival and disease-free survival.
| Characteristics | Overall survival | Disease-free survival | ||||||
|---|---|---|---|---|---|---|---|---|
| n | HR (95%CI) | P value | Heterogeneity | n | HR (95%CI) | P value | Heterogeneity | |
| Study type | ||||||||
| Retrospective | 17 | 1.73(1.43,2.08) | <0.001 | 63.1 | 11 | 1.41(1.25,1.50) | <0.001 | 50.8% |
| Prospective | 2 | 1.75(1.32,2.30) | <0.001 | 0.0% | 1 | 1.53(1.01,2.30) | 0.04 | NA |
| Patients number | ||||||||
| ≥200 | 10 | 1.39(1.20,1.62) | <0.001 | 48.5% | 6 | 1.33(1.17,1.51) | <0.001 | 6.6% |
| <200 | 9 | 2.57(1.92,3.45) | <0.001 | 19.2% | 6 | 1.93(1.47,2.55) | <0.001 | 0.0% |
| NOS scores | ||||||||
| >5 | 14 | 1.71(1.39,2.10) | <0.001 | 57.9% | 9 | 1.43(1.25,1.62) | <0.001 | 40.0% |
| ≤5 | 5 | 1.91(1.30,2.79) | 0.001 | 72.7% | 3 | 1.39(1.07,1.82) | 0.015 | 0.0% |
| Ethnicity | ||||||||
| Asian | 12 | 1.78(1.37,2.31) | <0.001 | 66.2% | 8 | 1.41(1.23,1.62) | <0.001 | 52.7% |
| Caucasian | 7 | 1.68(1.33,2.12) | <0.001 | 53.7% | 4 | 1.44(1.16,1.79) | 0.001 | 0.0% |
| Criterion of sarcopenia | ||||||||
| =1 | 15 | 1.93(1.51,2.47) | <0.001 | 66.4% | 9 | 1.40(1.23,1.60) | <0.001 | 20.5% |
| >1 | 4 | 1.41(1.21,1.63) | <0.001 | 14.2% | 3 | 1.50(1.16,1.95) | 0.002 | 74.7% |
| Tumor type | ||||||||
| Rectal cancer | 11 | 2.37(1.61,3.48) | <0.001 | 70.8% | 5 | 1.94(1.40,2.68) | <0.001 | 36.2% |
| Colorectal cancer | 8 | 1.42(1.26,1.65) | <0.001 | 31.0% | 7 | 1.36(1.20,2.42) | <0.001 | 0.0% |
HR, hazard radio; NA, not applicable.