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. 2023 Oct 27;13:1247341. doi: 10.3389/fonc.2023.1247341

Table 3.

Subgroup analyses in terms of overall survival and disease-free survival.

Characteristics Overall survival Disease-free survival
n HR (95%CI) P value Heterogeneity n HR (95%CI) P value Heterogeneity
Study type
Retrospective 17 1.73(1.43,2.08) <0.001 63.1 11 1.41(1.25,1.50) <0.001 50.8%
Prospective 2 1.75(1.32,2.30) <0.001 0.0% 1 1.53(1.01,2.30) 0.04 NA
Patients number
≥200 10 1.39(1.20,1.62) <0.001 48.5% 6 1.33(1.17,1.51) <0.001 6.6%
<200 9 2.57(1.92,3.45) <0.001 19.2% 6 1.93(1.47,2.55) <0.001 0.0%
NOS scores
>5 14 1.71(1.39,2.10) <0.001 57.9% 9 1.43(1.25,1.62) <0.001 40.0%
≤5 5 1.91(1.30,2.79) 0.001 72.7% 3 1.39(1.07,1.82) 0.015 0.0%
Ethnicity
Asian 12 1.78(1.37,2.31) <0.001 66.2% 8 1.41(1.23,1.62) <0.001 52.7%
Caucasian 7 1.68(1.33,2.12) <0.001 53.7% 4 1.44(1.16,1.79) 0.001 0.0%
Criterion of sarcopenia
=1 15 1.93(1.51,2.47) <0.001 66.4% 9 1.40(1.23,1.60) <0.001 20.5%
>1 4 1.41(1.21,1.63) <0.001 14.2% 3 1.50(1.16,1.95) 0.002 74.7%
Tumor type
Rectal cancer 11 2.37(1.61,3.48) <0.001 70.8% 5 1.94(1.40,2.68) <0.001 36.2%
Colorectal cancer 8 1.42(1.26,1.65) <0.001 31.0% 7 1.36(1.20,2.42) <0.001 0.0%

HR, hazard radio; NA, not applicable.