Fig. 65. FRET pH sensor. (A) FRET-DNA pH sensor using different D–A arrangements with 12 possible D and A positions. (B) Different FRET arrangements (pH-inert C343 D in green and pH-sensitive FAM A in red) on triangular DNA origami were used for ratiometric pH sensing. (C) A 3 × 4 checkerboard arrangement resulted in the best pH sensing performance. Reproduced with permission from ref. 429 Copyright 2018 American Chemical Society.
