Table 2.
Summary of DCF, IBU, and PAR biodegradation.
| Ent. | Microorganism | Isolation place | Drug | Biodegradation rate (conditions) | Ref |
|---|---|---|---|---|---|
| 1. | Brevibacterium sp. D4 | From wastwater treatment plant (Ponte de Moreira, Maia—Portugal) | DCF | 90% (10 mg L−1, at 25°C, 150 rpm by 30 days) | Bessa et al. (2017) |
| 2. | Labrys portucalensis F11 | From sediment of a polluted site in the northern Portugal | DCF | >99% (7.01 mg L−1 at 25°C, 130 rpm by 25 days) | Moreira et al. (2018) |
| 3. | Bacillus subtilis | Provided by the Prodibio Company—Marseille, France | DCF | >99% (1,000 mg L−1, at 20°C, 100 rpm by 17 h) | Grandclément et al. (2020) |
| 4. | Rhodococcus ruber IEGM 346 | From Regional Specialized Collection of Alkanotrophic Microorganisms | DCF | >99% (1,000 mg L−1, at 28°C, 100 rpm by 6 days and 0.5% glucose). | Ivshina et al. (2019) |
| 5. | Klebsiella sp. KSC | From livestock soil | DCF | 90% (70,000 mg L−1, at 30°C, pH 7, 100 rpm by 72 h) | Stylianou et al. (2018) |
| 6. | Microbial consortia | Native microbial soil | DCF | 90% (1,000 mg L −1, at 25°C, 120 rpm by 10 days) | Facey et al. (2018) |
| 7. | Ganoderma applanatum | Collection in the Department of Pure and Applied Botany—Nigeria | DCF | 61% (15 mg L−1, at 30°C, pH 4, 5 and 150 rpm by 72 h) | Bankole et al. (2020) |
| 8. | Laetiporus sulphureus | Collection in the Department of Pure and Applied Botany, Federal University of Agriculture Abeokuta—Nigeria | DCF | 73% (15 mg L−1, at 30°C, pH 4.5 and 150 rpm by 72 h) | Bankole et al. (2020) |
| 9. | Talaromyces gossypii | Sewage sludge composite samples were collected from the WWTPs—Granada—Spain | DCF | 84.6% (20.62 mg L−1 at 28°C by 72 h) | Conejo-Saucedo et al. (2021) |
| 10. | Syncephalastrum monosporum | Sewage sludge composite samples were collected from the WWTPs—Granada—Spain | DCF | 82% (20.62 mg L−1 at 28°C by 72 h) | Conejo-Saucedo et al. (2021) |
| 11. | Aspergillus tabacinus | Sewage sludge composite samples were collected from the WWTPs—Granada—Spain | DCF | 76% (20.62 mg L−1 at 28°C by 72 h) | Conejo-Saucedo et al. (2021) |
| 12. | Talaromyces verruculosus | Sewage sludge composite samples were collected from the WWTPs—Granada—Spain | DCF | 37% (20.62 mg L−1 at 28°C by 72 h) | Conejo-Saucedo et al. (2021) |
| 13. | Aspergillus terreus | Sewage sludge composite samples were collected from the WWTPs—Granada—Spain | DCF | 49,7% (20.62 mg L−1 at 28°C by 72 h) | Conejo-Saucedo et al. (2021) |
| 14. | Aspergillus cejpii | Sewage sludge composite samples were collected from the WWTPs—Granada—Spain | DCF | 14.6% (20.62 mg L−1 at 28°C by 72 h) | Conejo-Saucedo et al. (2021) |
| 15. | Microbial consortium (Alcaligenes faecalis, Staphylococcus aureus, Staphylococcus, haemolyticus, Proteus mirabilis) | Isolated from the vicinity of a pharmaceutical manufacturing unit—India | DCF | 45% (150 mg.L−1, at 25–30°C, pH 7 by 120 h) | Murshid and Dhakshinamoorthy (2019) |
| 16. | Penicillium oxalicum | Isolated from a hydrocarbonpolluted pond in Motril—Granada | DCF sodium | 99% (20.62 mg L−1, 24 h, 28°C) | Murshid and Dhakshinamoorthy (2019) |
| 17. | Rhizophagus irregularis | Institute of Botany, Czech Academy of Science—Czechia | IBU | 80% (0.5 mg L−1, 5–30°C, by 150 days,) | Hu et al. (2021) |
| 18. | Sphingopyxis granuli RW412 | River Elbe taken downstream of the Hamburg harbor-Germany | IBU | 80% (800 mg L−1, 30°C, 200 rpm, 3 days) | Aguilar-Romero et al. (2021) |
| 19. | Bacillus thuringiensis | Soil of the Chemical factory “Organika-Azot” in Jaworzno, Poland | IBU | 46.56% (25 mg L−1, at 30°C,130 rpm by 20 days) | Marchlewicz et al. (2016) |
| 20. | Patulibacter sp. Strain L11 | Activated sludge collected from Beirolas WWTP—(Lisbon, Portugal) | IBU | 92% (0.05 mg L−1, at 28°C, 110 rpm by 90 h) | Almeida et al. (2013a) |
| 21. | Gordonia amicalis EU266486.1 | Activated sludge Beirolas WWTP (Lisbon, Portugal) | IBU | 26% (0.1 mg L−1, at 27°C, 110 rpm by 100 h) | Almeida et al. (2013b) |
| 22. | Acinetobacter bouvetti JF681285 | Activated sludge Beirolas WWTP (Lisbon, Portugal) | IBU | 12.8% (0.1 mg L−1, at 27°C, 110 rpm by 100 h) | Almeida et al. (2013b) |
| 23. | Bacillus siamensis DSI-1 | Isolated from wastewater—GenBank MT 039503 | IBU | 50% (3.5 mg L-1, at 30°C, pH 7, 165 rpm, by 18 h) | Chopra and Kumar (2022) |
| 24. | Microbacterium paraoxydans | Isolated from pharmaceutical wastewater of East India Pharmaceutical Private Limited, Durgapur, West Bengal, India | IBU | 92,01% (15 mg L−1, at 30°C, pH 7, 150 rpm, 0.3% yeast extract) | Show et al. (2023) |
| 25. | Patulibacter medicamentivorans | Isolated from activated sludge collected from Beirolas WWTP (Lisbon, Portugal) | IBU | >99% (0.25 mg L−1, at 28°C, pH 7, 110 rpm by 7 days) | Salgado et al. (2020) |
| 26. | Nocardioides carbamazepini sp. nov. CBZ_1T | Biofilm sample collected from a Pump and Treat system treating BTEX (benzene, toluene, ethyl-benzene, and xylenes) contaminated groundwater | IBU | 70% (1.5 mg.L−1, at 27°C, 145 rpm by 7 days) | Benedek et al. (2022) |
| 27. | Sphingomonas wottichii MPO218 | Sewage sludge of Copero (EMASESA, dos Hermanas, Seville, Spain), Company Almirall (Barcelona Spain) | IBU | >75% (4.4 mM at 4.5 h, 30°C and pH 7) | Aulestia et al. (2021) |
| 28. | Sphingomonas sp | IBU | >99% (500 mg L−1, 80 h, 37 ± 2°C) | Murdoch and Hay, 2013 | |
| 29. | Pseudoalteromonas sp | GenBank accession number: KY583737 | IBU | 80%, (1.0 mg L−1, 20 ± 1°C, 150 rpm by 72 h) | Li et al. (2022) |
| 30. | Rhodococcus cerastii IEGM 1278 | Regional specialized Collection of Alkano-trophic Microorganisms (acronym IEGM, the wprdl Federation for Culture) | IBU | 14.1% (100 mg L−1, at 28°C, 160 rpm by 7 days) | Ivshina et al. (2021) |
| 31. | R. cercidiphylli IEGM 1184 | Regional specialized Collection of Alkano-trophic Microorganisms (acronym IEGM, the wprdl Federation for Culture) | IBU | 21.6% (100 mg L−1, at 28°C, 160 rpm by 7 days) | Ivshina et al. (2021) |
| 32. | R. erythropolis IEGM 501 | Regional specialized Collection of Alkano-trophic Microorganisms (acronym IEGM, the wprdl Federation for Culture) | IBU | 18.6% (100 mg L−1, at 28°C, 160 rpm by 7 days) | Ivshina et al. (2021) |
| 33. | Paracoccus aminophilus NR_042715.1 | Activated sludge Beirolas WWTP (Lisbon, Portugal) | IBU | 16.2% (0.1 mg L−1, at 27°C, 110 rpm by 100 h) | Almeida et al. (2013b) |
| 34. | Patulibacter americanus NR_042369 | Activated sludge Beirolas WWTP (Lisbon, Portugal) | IBU | 35% (0.1 mg L−1, at 27°C, 110 rpm by 100 h) | Almeida et al. (2013b) |
| 35. | Pseudomonas stutzeri CSW02 | Sewage sludge was obtained from a Wastewater Treatment Plant (WWTP) in the city of Seville | PAR | 100% (500 mg L−1, at 30 ± 1°C, 150 rpm by 4 h) | Vargas-Ordóñez et al. (2023) |
| 36. | Pseudomonas extremaustralis CSW01 | Sewage sludge was obtained from a Wastewater Treatment Plant (WWTP) in the city of Seville | PAR | 100% (500 mg L−1, at 30 ± 1°C, 150 rpm, by 6 h) | Vargas-Ordóñez et al. (2023) |
| 37. | Pseudomonas sp. PrS10 | Sample wastewater collected from Cadila Pharmaceutical Limited, Gujarat, India | PAR | 96.37% (3,000 mg L−1, at 30°C, 140 rpm by 7 days) | Poddar et al. (2022) |
| 38 | Pseudomonas moorei KB4 | From the activated sludge from the wastewater treatment plant Klimzowiec (Chorzów, Poland) | PAR | 99% (50 mg L−1, at 30°C, pH 7 by 1.5 h) | Żur et al. (2018b) |
| 39. | Pseudomonas aeruginosa | Sludges from two Portuguese WWTPs | PAR | 90% (50 mg L−1, at r.t, by 2 days) | Palma et al. (2018) |
| 40. | Pseudomonas sp. f2 | PAR-degrading aerobic aggregate | PAR | 100% (2.000 mg L−1, at 30°C, 200 rpm by 70 h) | Zhang et al. (2013) |
| 41. | Pseudomonas sp. fg-2 | PAR-degrading aerobic aggregate | PAR | 100% (2,500 mg L−1, 30°C, 200 rpm by 45 h) | Zhang et al. (2013) |
| 42. | Stenotrophomonas sp. f1 | PAR-degrading aerobic aggregate | PAR | 100% (2,000 mg L−1, at 30°C, 200 rpm, by 16 h) | Zhang et al. (2013) |
| 43. | Pseudomonas aeruginosa strain HJ1012 | Isolated from stable microbial aggregate in a sequencing batch reactor | PAR | 71.4% (2,200 mg L−1, at 30°C, pH 7 by 18 h) | Hu et al. (2013) |
| 44. | Aspergillus niger | Wastewater samples were collected from the effluent generated by YEDCO factory situated in Sana’a City, Yemen | PAR | 37% (2,000 mg L−1, at 25°C, pH 6.0 by 60 days) | Sana (2018) |
| 45. | Fusarium oxysporium | Wastewater samples were collected from the effluent generated by YEDCO factory situated in Sana’a City, Yemen | PAR | 26.1% (1,000 mg L−1, at 25°C, pH 6.0 by 60 days) | Sana (2018) |
| 46. | Microbial consortium (Bacillus cereus; Corynebacterium nuruki; Enterococcus faecium) | A sample of aerobic activated sludge was collected from the oxidation ditch of Faro Northwest WWTP’s, Portugal. | PAR | > 90% (200 mg L−1, at 28°C, by 48 h) | Palma et al. (2021) |
| 47. | Bacillus drentensis estirpe S1 | The sewage samples used in this study were collected from waste water drain in Sonipat, Haryana, India | PAR | 93% (300 mg L−1, at 40°C, pH 7, 165 rpm by 48 h) | Chopra and Kumar (2020) |
| 48. | M. yunnanensis KGP04 | Pharmaceutical industry wastewater and sludge samples were collected from VKIA (Vishwakarma Industrial Area), Jaipur | PAR | 80% (1% w/v, at 25°C, pH 8, 200 rpm, by 6 h) | Sharma et al. (2020) |
| 49. | M. yunnanensis TJPT4 | Bacteria recovered from marine organisms, which were collected from the Catedral and Queijo Suiço marine caves, located in Sagres, Algarve, Portugal | PAR | >60% (15 mg L−1, at 28°C, 150 rpm, by 360 h) | Palma et al. (2022) |
| 50. | Pseudomonas spp. | Sludge of a hospital WWTP (Pharmafilter, Delft, NL) | PAR | >99% [250 mgL−1 (reactor conditions 500 rpm, pH 7, airflow 30 mL/min, and 20 ± 1°C) at 10 days] | Rios-Miguel et al. (2022) |